Evidence map›Paper›PMID 34521189›Full record

ArticleZhongguo fei ai za zhi = Chinese journal of lung cancer2021

[Research Progress of Immune Checkpoint Inhibitor-associated Myocarditis].

Yunwei Liu, Yanxin Chen, Zhimin Zeng, Anwen Liu

Open access · greenAbstract read
In one paragraph

Article in Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yunwei LiuDepartment of Oncology, The Second Affiliated Hospital of Nanchang University, 
Jiangxi Key Laboratory of Clinical Translational Cancer Research, Nanchang 330006, China.
Yanxin ChenDepartment of Oncology, The Second Affiliated Hospital of Nanchang University, 
Jiangxi Key Laboratory of Clinical Translational Cancer Research, Nanchang 330006, China.
Zhimin ZengDepartment of Oncology, The Second Affiliated Hospital of Nanchang University, 
Jiangxi Key Laboratory of Clinical Translational Cancer Research, Nanchang 330006, China.
Anwen LiuDepartment of Oncology, The Second Affiliated Hospital of Nanchang University, 
Jiangxi Key Laboratory of Clinical Translational Cancer Research, Nanchang 330006, China.
Second Affiliated Hospital of Nanchang University · CNJiangxi Provincial Cancer Hospital · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune checkpoint inhibitors (ICIs) is a negative regulatory factor antibody, which activates T cells to play an anti-tumor effect in immunotherapy, and can also cause immune-related adverse responses, thereby inducing a series of immune related adverse events (irAEs). Among these irAEs, although the incidence of ICIs-related myocarditis is very low, the fatality rate is significantly higher than other adverse reactions, close to 50%. Clinicians should be vigilant when applying ICIs, but the pathogenesis of ICIs-related myocarditis is still unclear. This article combines the recent research results of ICIs to summarize the mechanism and clinical manifestations of ICIs-related myocarditis, so as to improve clinicians' understanding of the adverse reactions.
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Indexed as

Immune Checkpoint InhibitorsMyocarditisNeoplasmsBiomedical ResearchCardiotoxicityHumansImmunotherapyImmune Checkpoint InhibitorsCardiotoxicityImmune checkpoint inhibitorMyocarditis

Identifiers

PMID34521189
PMCPMC8503978
OpenAlexW3199985644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.