Evidence map›Paper›PMID 34521104›Full record

ArticleBlood advances2021

How to write a guideline: a proposal for a manuscript template that supports the creation of trustworthy guidelines.

Robby Nieuwlaat, Wojtek Wiercioch, Jan L Brozek, Nancy Santesso, Robert Kunkle, Pablo Alonso-Coello, David R Anderson, Shannon M Bates, Philipp Dahm, Alfonso Iorio and 12 more

Abstract read
In one paragraph

Article in Blood advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. The value of the old and the new.Blood advances · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Robby NieuwlaatMichael G. DeGroote Cochrane Canada and McMaster GRADE Centres and.
Wojtek WierciochMichael G. DeGroote Cochrane Canada and McMaster GRADE Centres and.ORCID 0000-0001-6576-1650
Jan L BrozekMichael G. DeGroote Cochrane Canada and McMaster GRADE Centres and.ORCID 0000-0002-3122-0773
Nancy SantessoMichael G. DeGroote Cochrane Canada and McMaster GRADE Centres and.ORCID 0000-0003-0550-4585
Robert KunkleAmerican Society of Hematology, Washington, DC.
Pablo Alonso-CoelloIberoamerican Cochrane Center, Biomedical Research Institute Sant Pau (IIB Sant Pau-CIBERESP), Barcelona, Spain.
David R AndersonDepartment of Medicine, Dalhousie University, Halifax, NS, Canada.
Shannon M BatesDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Philipp DahmUrology Section, Minneapolis VA Health Care System, Minneapolis, MN.ORCID 0000-0003-2819-2553
Alfonso IorioDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.ORCID 0000-0002-3331-8766
Wendy LimDepartment of Medicine, McMaster University, Hamilton, ON, Canada.ORCID 0000-0003-2508-1786
Gary H LymanDepartment of Medicine, Fred Hutchinson Cancer Research Center, University of Washington School of Medicine, Seattle, WA.
Saskia MiddeldorpDepartment of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, University of Amsterdam, The Netherlands.ORCID 0000-0002-1006-6420
Paul MonagleDepartment of Paediatrics, University of Melbourne, Melbourne, Australia.
Reem A MustafaDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Ignacio NeumannDepartment of Internal Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.
Thomas L OrtelDepartment of Medicine.
Bram RochwergDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Sara K VeselyDepartment of Biostatistics and Epidemiology, Hudson College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK.ORCID 0000-0003-3448-0156
Daniel M WittDepartment of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, UT.ORCID 0000-0002-3930-8358
Adam CukerDepartment of Medicine; and.ORCID 0000-0002-3595-5697
Holger J SchünemannMichael G. DeGroote Cochrane Canada and McMaster GRADE Centres and.ORCID 0000-0003-3211-8479

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trustworthy health guidelines should provide recommendations, document the development process, and highlight implementation information. Our objective was to develop a guideline manuscript template to help authors write a complete and useful report. The McMaster Grading of Recommendations Assessment, Development and Evaluation Centre collaborated with the American Society of Hematology (ASH) to develop guidelines for the management of venous thromboembolism. A template for reporting the guidelines was developed based on prior approaches and refined using input from other key stakeholders. The proposed guideline manuscript template includes: (1) title for guideline identification, (2) abstract, including a summary of key recommendations, (3) overview of all recommendations (executive summary), and (4) the main text, providing sufficient detail about the entire process, including objectives, background, and methodological decisions from panel selection and conflict-of-interest management to criteria for updating, as well as supporting information, such as links to online (interactive) tables. The template further allows for tailoring to the specific topic, using examples. Initial experience with the ASH guideline manuscript template was positive, and challenges included drafting descriptions of recommendations involving multiple management pathways, tailoring the template for a specific guideline, and choosing key recommendations to highlight. Feedback from a larger group of guideline authors and users will be needed to evaluate its usefulness and refine. The proposed guideline manuscript template is the first detailed template for transparent and complete reporting of guidelines. Consistent application of the template may simplify the preparation of an evidence-based guideline manuscript and facilitate its use.

Indexed as

Practice Guidelines as TopicVenous ThromboembolismHumansTrust

Identifiers

PMID34521104
PMCPMC8759117

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.