ArticleJournal of the Royal Society, Interface2021
Hyperendemicity associated with increased dengue burden.
Article in Journal of the Royal Society, Interface, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The epidemiologic and economic burden of dengue in Singapore: A systematic review.PLoS neglected tropical diseases · 2024Pooled it
- Proactive Initiative to Establish a Dengue-Free Factory Assessment Framework in Dengue High-Risk Industrial Areas: A Narrative Review.Interdisciplinary perspectives on infectious diseases · 2026Review
- Pre- and post-COVID-19 pandemic identification of dengue hotspots and exploration of population and environmental determinants of dengue in Quezon City, Philippines.Tropical medicine and health · 2025Article
- Annual global dengue dynamics are related to multi-source factors revealed by a machine learning prediction analysis.PLoS neglected tropical diseases · 2025Article
- Public Health Messaging About Dengue on Facebook in Singapore During the COVID-19 Pandemic: Content Analysis.JMIR formative research · 2025Article
- Article
- Singapore's Dengue Outbreak Amidst the COVID-19 Pandemic: Challenges, Responses, and Lessons.Infection and drug resistance · 2023Article
- Article
- Review of Importance of Weather and Environmental Variables in Agent-Based Arbovirus Models.International journal of environmental research and public health · 2022Review
- Fine-scale estimation of effective reproduction numbers for dengue surveillance.PLoS computational biology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over 105 million dengue infections are estimated to occur annually. Understanding the disease dynamics of dengue is often difficult due to multiple strains circulating within a population. Interactions between dengue serotype dynamics may result in complex cross-immunity dynamics at the population level and create difficulties in terms of formulating intervention strategies for the disease. In this study, a nationally representative 16-year time series with over 43 000 serotyped dengue infections was used to infer the long-run effects of between and within strain interactions and their impacts on past outbreaks. We used a novel identification strategy incorporating sign-identified Bayesian vector autoregressions, using structural impulse responses, historical decompositions and counterfactual analysis to conduct inference on dengue dynamics post-estimation. We found that on the population level: (i) across-serotype interactions on the population level were highly persistent, with a one time increase in any other serotype associated with long run decreases in the serotype of interest (range: 0.5-2.5 years) and (ii) over 38.7% of dengue cases of any serotype were associated with across-serotype interactions. The findings in this paper will substantially impact public health policy interventions with respect to dengue.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.