Evidence map›Paper›PMID 34520634›Full record

ReviewBrain and behavior2021

Optical coherence tomography monitoring and diagnosing retinal changes in multiple sclerosis.

Arshad Mehmood, Wajid Ali, Shuang Song, Zaheer Ud Din, Ruo-Yi Guo, Wahid Shah, Ikram Ilahi, Bowen Yin, Hongjing Yan, Lu Zhang and 5 more

Abstract readReview
In one paragraph

Review in Brain and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Arshad MehmoodDepartment of Neurology, The Second Hospital of Hebei Medical University, City Shijiazhuang, Hebei Province, P. R. China.
Wajid AliKey Laboratory of Functional Inorganic Materials Chemistry, School of Chemistry and Materials Science, Heilongjiang University, Harbin, P. R. China.
Shuang SongDepartment of Neurology, The Second Hospital of Hebei Medical University, City Shijiazhuang, Hebei Province, P. R. China.
Zaheer Ud DinInstitute of Cancer Stem Cell, Dalian Medical University, Liaoning Province, P. R. China.
Ruo-Yi GuoDepartment of Neurology, The Second Hospital of Hebei Medical University, City Shijiazhuang, Hebei Province, P. R. China.
Wahid ShahDepartment of Physiology, Hebei Medical University, Shijiazhuang, Hebei, P. R. China.
Ikram IlahiDepartment of Zoology, University of Malakand, Chakdara, Khyber Pakhtunkhwa, Pakistan.
Bowen YinDepartment of Neurology, The Second Hospital of Hebei Medical University, City Shijiazhuang, Hebei Province, P. R. China.
Hongjing YanDepartment of Neurology, The Second Hospital of Hebei Medical University, City Shijiazhuang, Hebei Province, P. R. China.
Lu ZhangDepartment of Neurology, The Second Hospital of Hebei Medical University, City Shijiazhuang, Hebei Province, P. R. China.
Murad KhanDepartment of Genetics, Hebei Key Lab of Laboratory Animal, Hebei Medical University, Shijiazhuang, Hebei Province, P. R. China.
Wajid AliGreen and Environmental Chemistry, Ecotoxicology and Ecology Laboratory, Department of Zoology, University of Malakand, Chakdara, Khyber Pakhtunkhwa, Pakistan.
Liaqat ZebSchool of Bioengineering, Dalian University of Technology, Dalian, Liaoning, P.R. China.
Hamidreza SafariDepartment of Immunology, Torbat Jam Faculty of Medical Sciences, Torbat Jam, Iran.
Bin LiDepartment of Neurology, The Second Hospital of Hebei Medical University, City Shijiazhuang, Hebei Province, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explores the use of optical coherence tomography (OCT) to monitor and diagnose multiple sclerosis (MS). The analysis of reduced total macular volume and peripapillary retinal nerve fiber layer thinning are shown. The severity of these defects increases as MS progresses, reflecting the progressive degeneration of nerve fibers and retinal ganglion cells. The OCT parameters are noninvasive, sensitive indicators that can be used to assess the progression of neurodegeneration and inflammation in MS.

Indexed as

Multiple SclerosisTomography, Optical CoherenceHumansNerve FibersRetinaRetinal Ganglion Cellsexperimental autoimmune encephalomyelitisganglion cell layermultiple sclerosisoptical coherence tomographyretinal nerve fiber layer

Identifiers

PMID34520634
PMCPMC8553325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.