ArticlePloS one2021
Dengue virus in humans and mosquitoes and their molecular characteristics in northeastern Thailand 2016-2018.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Epidemiological Characteristics of Dengue Infection in Bangladesh: A Systematic Review.International journal of environmental research and public health · 2026Pooled it
- Systematic review and meta-analysis of virome profiles and quantification of Torque teno virus load in blood of acute febrile illness patients.Scientific reports · 2025Pooled it
- Dengue virus genetic diversity and lineage dynamics in Thailand: implications for surveillance and vaccine implementation.Virology journal · 2026Article
- Mapping landscape changes to address dengue fever risk in Laos and Thailand.Current research in parasitology & vector-borne diseases · 2026Article
- Computational repurposing of drugs against dengue virus targeting NS5 and methyltransferase proteins.Scientific reports · 2025Article
- Prevalence and characteristics of dengue virus co-infection in patients and mosquitoes collected from patients' houses.PloS one · 2025Article
- Development of an Enzyme-Linked Immunosorbent Assay (ELISA) as a tool to detect NS1 of dengue virus serotype 2 in femaleHeliyon · 2024Article
- Repellents againstFrontiers in insect science · 2024Review
- The 2022 dengue outbreak in Bangladesh: hypotheses for the late resurgence of cases and fatalities.Journal of medical entomology · 2023Article
- Review
- Article
- Therapeutic Potential of Medicinal Plants against Dengue Infection: A Mechanistic Viewpoint.ACS omega · 2022Review
- Entomological Investigation and Detection of Dengue Virus Type 1 inFrontiers in cellular and infection microbiology · 2022Article
- Comparison of Fan-Traps and Gravitraps forFrontiers in public health · 2022Article
- Concurrent dengue infections: Epidemiology & clinical implications.The Indian journal of medical research · 2021Review
- Getting dengue from vector mosquito bite at home: a reappraisal on chance based on molecular epidemiology data in Indochina.International journal of molecular epidemiology and genetics · 2021Article
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Authors and funding
14 authors.
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Abstract
Dengue is hyperendemic in most Southeast Asian countries including Thailand, where all four dengue virus serotypes (DENV-1 to -4) have circulated over different periods and regions. Despite dengue cases being annually reported in all regions of Thailand, there is limited data on the relationship of epidemic DENV infection between humans and mosquitoes, and about the dynamics of DENV during outbreaks in the northeastern region. The present study was conducted in this region to investigate the molecular epidemiology of DENV and explore the relationships of DENV infection in humans and in mosquitoes during 2016-2018. A total of 292 dengue suspected patients from 11 hospitals and 902 individual mosquitoes (at patient's houses and neighboring houses) were recruited and investigated for DENV serotypes infection using PCR. A total of 103 patients and 149 individual mosquitoes were DENV -positive. Among patients, the predominant DENV serotypes in 2016 and 2018 were DENV-4 (74%) and DENV-3 (53%) respectively, whereas in 2017, DENV-1, -3 and -4 had similar prevalence (38%). Additionally, only 19% of DENV infections in humans and mosquitoes at surrounding houses were serotypically matched, while 81% of infections were serotypically mismatched, suggesting that mosquitoes outside the residence may be an important factor of endemic dengue transmission. Phylogenetic analyses based on envelope gene sequences showed the genotype I of both DENV-1 and DENV-4, and co-circulation of the Cosmopolitan and Asian I genotypes of DENV-2. These strains were closely related to concurrent strains in other parts of Thailand and also similar to strains in previous epidemiological profiles in Thailand and elsewhere in Southeast Asia. These findings highlight genomic data of DENV in this region and suggest that people's movement in urban environments may result in mosquitoes far away from the residential area being key determinants of DENV epidemic dynamics.
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