Evidence map›Paper›PMID 34520354›Full record

ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2022

3-D Stochastic Numerical Breast Phantoms for Enabling Virtual Imaging Trials of Ultrasound Computed Tomography.

Fu Li, Umberto Villa, Seonyeong Park, Mark A Anastasio

Abstract read
In one paragraph

Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  6. Survey of Deep Learning and Physics-Based Approaches in Computational Wave Imaging.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2025
    Article
  7. Deep-Learning-Driven High Spatial Resolution Attenuation Imaging for Ultrasound Tomography (AI-UT).IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025
    Article
  8. Review
  9. Article
  10. 3D Frequency-Domain Full Waveform Inversion for Whole-Breast Imaging With a Multi-Row Ring Array.IEEE open journal of ultrasonics, ferroelectrics, and frequency control · 2025
    Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fu Li
Umberto Villa
Seonyeong Park
Mark A Anastasio

Funding

Safe, rapid & functional pediatric brain imaging using photoacoustic computed tomographyR01NS102213 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ANASTASIO, MARK A, WANG, LIHONG · 2017 to 2021
$3.0M
A Computational Framework Enabling Virtual Imaging Trials of 3D Quantitative Optoacoustic Tomography Breast ImagingR01EB031585 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI ANASTASIO, MARK A · 2022 to 2025
$2.3M
Advanced image reconstruction for accurate and high-resolution breast ultrasound tomographyR01EB028652 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI ANASTASIO, MARK A, DURIC, NEBOJSA · 2019 to 2022
$2.2M
NIBIB NIH HHS R01 EB028652NIBIB NIH HHS R01 EB031585NINDS NIH HHS R01 NS102213
6 · The paper itself

Abstract

Ultrasound computed tomography (USCT) is an emerging imaging modality for breast imaging that can produce quantitative images that depict the acoustic properties of tissues. Computer-simulation studies, also known as virtual imaging trials, provide researchers with an economical and convenient route to systematically explore imaging system designs and image reconstruction methods. When simulating an imaging technology intended for clinical use, it is essential to employ realistic numerical phantoms that can facilitate the objective, or task-based, assessment of image quality (IQ). Moreover, when computing objective IQ measures, an ensemble of such phantoms should be employed, which displays the variability in anatomy and object properties that are representative of the to-be-imaged patient cohort. Such stochastic phantoms for clinically relevant applications of USCT are currently lacking. In this work, a methodology for producing realistic 3-D numerical breast phantoms for enabling clinically relevant computer-simulation studies of USCT breast imaging is presented. By extending and adapting an existing stochastic 3-D breast phantom for use with USCT, methods for creating ensembles of numerical acoustic breast phantoms are established. These breast phantoms will possess clinically relevant variations in breast size, composition, acoustic properties, tumor locations, and tissue textures. To demonstrate the use of the phantoms in virtual USCT studies, two brief case studies are presented, which addresses the development and assessment of image reconstruction procedures. Examples of breast phantoms produced by use of the proposed methods and a collection of 52 sets of simulated USCT measurement data have been made open source for use in image reconstruction development.

Indexed as

AlgorithmsTomography, X-Ray ComputedBreastFemaleHumansPhantoms, ImagingUltrasonography

Identifiers

PMID34520354
PMCPMC8790767

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.