Trial reportJournal of child and adolescent psychopharmacology2021
A Randomized, Double-Blind, Controlled Trial of Lithium Versus Quetiapine for the Treatment of Acute Mania in Youth with Early Course Bipolar Disorder.
Trial report in Journal of child and adolescent psychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Use of Lithium in Pediatric Bipolar Disorders and Externalizing Childhood- related Disorders: A Systematic Review of Randomized Controlled Trials.Current neuropharmacology · 2023Pooled it
- Trial
- Brain structural connectomic topology predicts medication response in youth with bipolar disorder: A randomized clinical trial.Journal of affective disorders · 2025Trial
- Pretreatment Alterations and Acute Medication Treatment Effects on Brain Task-Related Functional Connectivity in Youth With Bipolar Disorder: A Neuroimaging Randomized Clinical Trial.Journal of the American Academy of Child and Adolescent Psychiatry · 2022Trial
- Effect of Dosage Forms on the Steady-State Dose-Corrected Plasma Concentrations of Quetiapine and N-Desalkylquetiapine.Drug design, development and therapy · 2026Article
- Changes in ventral prefrontal-subcortical network connectivity during the course of remission from bipolar mania.Journal of mood and anxiety disorders · 2025Article
- Challenging the Safety Threshold: Neurotoxicity in Bipolar Disorder Treatment with Lithium at Therapeutic Serum Levels.Psychiatry and clinical psychopharmacology · 2025Article
- Pediatric Bipolar Disorder: Challenges in Diagnosis and Treatment.Paediatric drugs · 2025Review
- Efficacy and Safety of Lithium for Suicide and Suicide-Related Behaviors in Youth: A Review of the Literature.Brain sciences · 2024Review
- Morphological abnormalities in youth with bipolar disorder and their relationship to clinical characteristics.Journal of affective disorders · 2023Article
- A systematic review of interventions in the early course of bipolar disorder I or II: a report of the International Society for Bipolar Disorders Taskforce on early intervention.International journal of bipolar disorders · 2023Review
- Psychopharmacological Treatment Algorithms of Manic/Mixed and Depressed Episodes in Pediatric Bipolar Disorder.Journal of child and adolescent psychopharmacology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.