Evidence map›Paper›PMID 34520243›Full record

Observational studyThe British journal of radiology2021

Association between pericoronary adipose tissue attenuation and outcome after second-generation cryoballoon ablation for atrial fibrillation.

Kai Nogami, Tomoyo Sugiyama, Yoshihisa Kanaji, Masahiro Hoshino, Satoshi Hara, Masao Yamaguchi, Masahiro Hada, Yohei Sumino, Toru Misawa, Hidenori Hirano and 6 more

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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  4. Article
  5. Cardiac CT for electrophysiological interventions.The international journal of cardiovascular imaging · 2025
    Review
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Kai NogamiDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Tomoyo SugiyamaDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Yoshihisa KanajiDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Masahiro HoshinoDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Satoshi HaraDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Masao YamaguchiDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Masahiro HadaDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Yohei SuminoDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Toru MisawaDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Hidenori HiranoDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Hiroki UenoDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Naoyuki MiwaDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Kazuya YamaoDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Shigeki KusaDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Hitoshi HachiyaDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Tsunekazu KakutaDepartment of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Tsuchiura Kyodo General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPrevious studies reported the association between inflammation and atrial fibrillation (AF). Pericoronary adipose tissue (PCAT) attenuation, PCATA, on cardiac CT angiography (CTA) reflects pericoronary inflammation. We hypothesized that the PCATA predicts AF recurrence after cryoballoon ablation (CBA) for paroxysmal and persistent AF.

methodsWe studied 364 patients (median age, 65 years) with persistent (

resultsAF recurrence after the 3-month blanking period was detected in 90 patients (24.7%) during the median follow-up of 26 (interquartile range, 19-42) months. AF recurrence was associated with prior stroke and statin use, NT-proBNP and high-sensitivity cardiac troponin-I levels, left ventricular dimension, left atrial volume index (LAVI), 3V-PCATA, and early AF recurrence during the blanking period. On multivariable Cox proportional hazard analysis, prior stroke (hazard ratio [HR], 2.208, 95% confidence interval [CI], 1.166-4.180,

conclusionPre-ablation CTA-derived 3V-PCATA, representing pericoronary inflammation, was an independent predictor of recurrence after first-session AF ablation using a second-generation cryoballoon. ADVANCES IN KNOWLEDGE: Assessment of 3V-PCATA may identify patients at high risk of AF recurrence after CBA for AF.

Indexed as

Adipose TissueAgedAtrial FibrillationComputed Tomography AngiographyCryosurgeryFemaleHeartHumansMaleMiddle AgedRetrospective StudiesTreatment Outcome

Identifiers

PMID34520243
PMCPMC8631036
OpenAlexW3200529889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.