Evidence map›Paper›PMID 34520085›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Evaporation-Induced Self-Assembly of Small Peptide-Conjugated Silica Nanoparticles.

Cornelia von Baeckmann, Guilherme M D M Rubio, Hanspeter Kählig, Dennis Kurzbach, Michael R Reithofer, Freddy Kleitz

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Evaporation of a Reactive Nanofluid Sessile Drop:Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  3. Review
  4. Review
  5. Evaporation-Induced Self-Assembly of Small Peptide-Conjugated Silica Nanoparticles.Angewandte Chemie (International ed. in English) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cornelia von BaeckmannDepartment of Inorganic Chemistry-Functional Materials, Faculty of Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria.ORCID 0000-0002-2337-9063
Guilherme M D M RubioDepartment of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria.ORCID 0000-0002-6889-0703
Hanspeter KähligDepartment of Organic Chemistry, Faculty of Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria.ORCID 0000-0002-3898-6501
Dennis KurzbachDepartment of Biological Chemistry, Faculty of Chemistry, University of Vienna, Wahringer Straße 38, 1090, Vienna, Austria.ORCID 0000-0001-6455-2136
Michael R ReithoferDepartment of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria.ORCID 0000-0002-6328-1896
Freddy KleitzDepartment of Inorganic Chemistry-Functional Materials, Faculty of Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria.ORCID 0000-0001-6769-4180

Funding

FWF Der Wissenschaftsfonds P-33338H2020 European Research Council 801936University of Vienna
6 · The paper itself

Abstract

Self-assembly processes guide disordered molecules or particles into long-range organized structures due to specific supramolecular interactions among the building entities. Herein, we report a unique evaporation-induced self-assembly (EISA) strategy for four different silica nanoparticle systems obtained through peptide functionalization of the particle surface. First, covalent peptide-silica coupling was investigated in detail, starting with the grafting of a single amino acid (L-serine) and expanded to specific small peptides (up to four amino acids) and transferred to different particle types (MCM-48-type MSNs, solid nanoparticles, and newly developed virus-like nanoparticles). These materials were investigated regarding their ability to undergo EISA, which was shown to be independent of particle type and amount of peptide anchored to their surface. This EISA-based approach provides new possibilities for the design of future advanced drug delivery systems, engineered hierarchical sorbents, and nanocatalyst assemblies.

Indexed as

conjugationEISApeptidesself-organizationsilica nanoparticlessolid-state NMR

Identifiers

PMID34520085
PMCPMC8519068

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.