ArticleMedical physics2021
Quantitative lung perfusion blood volume using dual energy CT-based effective atomic number (Z
Article in Medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The trial behind it
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Who cites it
9 citing papers in PubMed, 28 citations in OpenAlex.
- Vascular attenuation and volumetric lung iodine density in dual-layer spectral CT pulmonary angiography: a randomized controlled trial comparing three contrast doses.European radiology · 2026Trial
- Feasibility of lung imaging at 0.55T for assessment of interstitial lung disease in patients with pulmonary sarcoidosis.European radiology · 2026Article
- Photon-counting CT for dynamic lung perfusion: validation of a low-dose protocol in a porcine lung transplantation model.European radiology experimental · 2026Article
- Accurate iodine quantification and residual error reduction with principal component analysis multimaterial decomposition using spectral CT.Medical physics · 2026Article
- Spectral CT quantitative parameters for predicting complete ablation after radiofrequency ablation in liver tumors: a retrospective study.Frontiers in oncology · 2026Article
- Investigating Patients with Pulmonary Hypertension Under Detector-Based Spectral Computed Tomography.Diagnostics (Basel, Switzerland) · 2025Article
- Pulmonary emphysema: the assessment of lung perfusion with Dual-Energy CT and pulmonary scintigraphy.La Radiologia medica · 2024Article
- A review on functional lung avoidance radiotherapy plan for lung cancer.Frontiers in oncology · 2024Review
- Clinical Applications of Photon-counting CT: A Review of Pioneer Studies and a Glimpse into the Future.Radiology · 2023Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIodine material images (aka iodine basis images) generated from dual energy computed tomography (DECT) have been used to assess potential perfusion defects in the pulmonary parenchyma. However, iodine material images do not provide the needed absolute quantification of the pulmonary blood pool, as materials with effective atomic numbers (Z PURPOSE: (i) To demonstrate the limitations of iodine material images in pulmonary perfusion defect quantification and (ii) to develop and validate a new quantitative biomarker using effective atomic numbers derived from DECT images.
methodsThe quantitative relationship between the perfusion blood volume (PBV) in pulmonary parenchyma and the effective atomic number (Z
resultsAmong patients with pulmonary emboli, the proposed
conclusionEffective atomic number-based quantitative PBV maps provide the needed sensitive and specific biomarker to quantify pulmonary perfusion defects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.