Evidence map›Paper›PMID 34519995›Full record

ReviewClinical reviews in allergy & immunology2022

Clinical Manifestations of Pediatric Food Allergy: a Contemporary Review.

Ling-Jen Wang, Shu-Chi Mu, Ming-I Lin, Tseng-Chen Sung, Bor-Luen Chiang, Cheng-Hui Lin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical reviews in allergy & immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. A comprehensive summary of disease variants implicated in metal allergy.Journal of toxicology and environmental health. Part B, Critical reviews · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ling-Jen WangDepartment of Pediatrics, Shin Kong WHS Memorial Hospital, Taipei, Taiwan.
Shu-Chi MuDepartment of Pediatrics, Shin Kong WHS Memorial Hospital, Taipei, Taiwan.
Ming-I LinDepartment of Pediatrics, Shin Kong WHS Memorial Hospital, Taipei, Taiwan.
Tseng-Chen SungDepartment of Pediatrics, Shin Kong WHS Memorial Hospital, Taipei, Taiwan.
Bor-Luen ChiangDepartment of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
Cheng-Hui LinDepartment of Pediatrics, Shin Kong WHS Memorial Hospital, Taipei, Taiwan. chlin2000@gmail.com.
Shin Kong WHS Memorial Hospital · TWNational Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food allergies (FAs) are an emerging health care issue, and a "second wave of the allergy epidemic" was named. There are extensive data that documented the prevalence rate as high as approximately 10%. FAs are immunological adverse reactions, including IgE-mediated mechanisms, cell-mediated mechanisms, or mixed IgE- and cell-mediated mechanisms. A diagnosis of FA is made by specific symptoms encounter with food, detailed past history, sensitization tests, and oral food challenges (OFCs) if necessary. The component-resolved diagnostics (CRD) test can distinguish true or cross-reaction. "Minimal elimination" from the results of CRD and OFC could avoid unnecessary food restriction. Strict food limitation is harsh and stressful on patients and their families. Children with FAs experience a higher rate of post-traumatic stress symptoms (PTSS) and bullying than others. In the last 20 years, oral immunotherapy (OIT), sublingual immunotherapy (SLIT), and epicutaneous immunotherapy (EPIT) are treatment strategies. OIT and EPIT are the most two encouraging treatments for FA. This review aims to introduce FAs in diverse clinical disorders, new perspectives, and their practical implications in diagnosing and treating FA.

Indexed as

Food HypersensitivitySublingual ImmunotherapyAllergensChildDesensitization, ImmunologicFoodHumansAllergensAllergen-specific immunoglobulin E (allergen-sIgE)Component-resolved diagnostics (CRD)Food allergy (FA)ImmunotherapyOral food challenge (OFC)

Identifiers

PMID34519995
OpenAlexW3200016447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.