Evidence map›Paper›PMID 34519760›Full record

ArticleJornal brasileiro de nefrologia

Relationship between quadriceps thickness and 60-second sit-to-stand test in patients with chronic kidney disease.

Marthley J C Costa, Frederico C B Cavalcanti, Shirley Dias Bezerra, José Candido de Araújo Filho, Juliana Fernandes, Patrícia E M Marinho

Abstract read
In one paragraph

Article in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Addition of Neuromuscular Electrical Stimulation, Based on the Level of Excitability, to an Intradialytic Twice-Weekly Cycling Protocol: A Randomized Trial.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Trial
  2. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Marthley J C CostaUniversidade Federal de Pernambuco, Departamento de Fisioterapia, Programa de Pós-Gradução em Fisioterapia, Recife, PE, Brasil.ORCID http://orcid.org/0000-0002-2489-127X
Frederico C B CavalcantiReal Hospital Português de Beneficência em Pernambuco, Unidade de Nefrologia, Recife, PE, Brasil.ORCID http://orcid.org/0000-0001-9778-8823
Shirley Dias BezerraUniversidade Federal de Pernambuco, Departamento de Fisioterapia, Programa de Pós-Gradução em Fisioterapia, Recife, PE, Brasil.ORCID http://orcid.org/0000-0002-2910-4685
José Candido de Araújo FilhoUniversidade Federal de Pernambuco, Departamento de Fisioterapia, Programa de Pós-Gradução em Fisioterapia, Recife, PE, Brasil.ORCID http://orcid.org/0000-0002-3941-3043
Juliana FernandesUniversidade Federal de Pernambuco, Departamento de Fisioterapia, Laboratório de Fisioterapia e Saúde Pública, Recife, PE, Brasil.ORCID http://orcid.org/0000-0002-7509-8853
Patrícia E M MarinhoUniversidade Federal de Pernambuco, Departamento de Fisioterapia, Programa de Pós-Gradução em Fisioterapia, Recife, PE, Brasil.ORCID http://orcid.org/0000-0002-3093-7481

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to evaluate the relationship between quadriceps muscle thickness and functional performance on the 60s sit-to-stand test (60s-STS), the six-minute walk test (6MWT), and handgrip strength in non-dialytic stage 4 and 5 chronic kidney disease (CKD) patients.

methodsThis was a cross-sectional study that evaluated 40 CKD patients aged between 30-70 years. Participants were submitted to an assessment that included quadriceps muscle thickness evaluated by a portable ultrasound. Functional performance tests included the 60s-STS, distance walked in the 6MWT, and handgrip strength. Also, body composition evaluated using electrical bioimpedance analysis and physical activity level through the short version of International Physical Activity were measured. Multiple linear regression was used to investigate the relationship between the quadriceps thickness and functional performance.

resultsQuadriceps muscle thickness was correlated to 60s-STS (R2 = 43.6%; 95% CI = 0.022 - 0.665; β = 0.34; p = 0.037). Also, a moderate correlation between this muscle thickness and appendicular skeletal muscle (ALM) was found in CKD patients (r = 0.603, p <0.001). No relationship was found between quadriceps muscle thickness with the 6MWT and handgrip strength.

conclusionQuadriceps muscle thickness is associated to 60s-STS, thus our results demonstrate the repercussions of the disease on the musculoskeletal system.

Indexed as

Quadriceps MuscleRenal Insufficiency, ChronicAdultAgedCross-Sectional StudiesHand StrengthHumansMiddle AgedWalk Test

Identifiers

PMID34519760
PMCPMC9269191

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.