Trial reportMedicine and science in sports and exercise2021
Effect of Aerobic Exercise-induced Weight Loss on the Components of Daily Energy Expenditure.
Trial report in Medicine and science in sports and exercise, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Impact of aerobic training on body composition profiles among postmenopausal women with overweight or obesity: a systematic review and dose-response meta-analysis.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Effects of aerobic exercise on body composition in children and adolescents with overweight and obesity: a systematic review and meta-analysis of randomized controlled trials.BMC public health · 2025Pooled it
- Comparing exercise modalities during caloric restriction: a systematic review and network meta-analysis on body composition.Frontiers in nutrition · 2025Pooled it
- Effect of resistance circuit training on comprehensive health indicators in older adults: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Exercise-induced compensation and C-reactive protein change in adults with elevated C-reactive protein: analysis of a randomised controlled trial.European journal of applied physiology · 2026Article
- Energy constraint on human health.Trends in endocrinology and metabolism: TEM · 2026Review
- Multilevel metabolic adaptation to exercise training.Communications medicine · 2026Article
- Structured Sanda training as an innovative exercise intervention for young men with obesity: metabolic load distribution and adaptive responses compared with moderate-intensity continuous cycling.Frontiers in sports and active living · 2026Article
- Physical activity substitution: An overlooked constraint on energy expenditure during exercise and physical activity interventions.Diabetes, obesity & metabolism · 2025Article
- Resting metabolic rate and energy efficiency in response to an intensive 84-day combat-swimmer training in the German Armed Forces.European journal of applied physiology · 2025Article
- Unraveling the multifaceted benefits of physical exercise: a comprehensive review of body composition, metabolic regulation, and systemic health.Frontiers in nutrition · 2025Review
- Association between physical activity and visceral adiposity index (VAI) in U.S. population with overweight or obesity: a cross-sectional study.BMC public health · 2024Article
- Article
- Development of Oral In Situ Gelling Liquid Formulations of Garcinia Extract for Treating Obesity.Gels (Basel, Switzerland) · 2023Article
- Exercise Is Medicine: How Do We Implement It?Nutrients · 2023Article
- Perspective: Is the Response of Human Energy Expenditure to Increased Physical Activity Additive or Constrained?Advances in nutrition (Bethesda, Md.) · 2023Article
- The Effects of an Acute Bout of Aerobic or Resistance Exercise on Nonexercise Physical Activity.Exercise, sport & movement · 2023Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
introductionExercise usually results in less weight loss than expected. This suggests increased energy intake and/or deceased expenditure counteract the energy deficit induced by exercise. The aim of this study was to evaluate changes in components of daily energy expenditure (doubly labeled water and room calorimetry) after 24 wk of exercise training with two doses of aerobic exercise.
methodsThis was an ancillary study in 42 (29 women, 13 men) sedentary, middle-age (47.8 ± 12.5 yr) individuals with obesity (35 ± 3.7 kg·m-2) enrolled in the Examination of Mechanisms of Exercise-induced Weight Compensation study. Subjects were randomized to three groups: healthy living control group (n = 13), aerobic exercise that expended 8 kcal·kg-1 of body weight per week (8 KKW, n = 14), or aerobic exercise that expended 20 kcal per kilogram of weight per week (20 KKW, n = 15). Total daily energy expenditure (TDEE) was measured in free-living condition by doubly labeled water and in sedentary conditions in a metabolic chamber over 24 h (24EE). Energy intake was calculated over 14 d from TDEE before and after the intervention using the intake-balance method.
resultsSignificant weight loss occurred with 20 KKW (-2.1 ± 0.7 kg, P = 0.04) but was only half of expected. In the 20 KKW group free-living TDEE increased by ~4% (P = 0.03), which is attributed to the increased exercise energy expenditure (P = 0.001), while 24EE in the chamber decreased by ~4% (P = 0.04). Aerobic exercise at 8 KKW did not induce weight change, and there was no significant change in any component of EE. There was no significant change in energy intake for any group (P = 0.53).
conclusionsStructured aerobic exercise at a dose of 20 KKW produced less weight loss than expected possibly due to behavioral adaptations leading to reduced 24EE in a metabolic chamber without any change in energy intake.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.