Evidence map›Paper›PMID 34519530›Full record

ArticlemSystems2021

Nitric Oxide Impacts Human Gut Microbiota Diversity and Functionalities.

Marion Leclerc, Cassandre Bedu-Ferrari, Lucie Etienne-Mesmin, Mahendra Mariadassou, Lucie Lebreuilly, Seav-Ly Tran, Laurence Brazeau, Camille Mayeur, Julien Delmas, Olivier Rué and 3 more

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Marion LeclercUniversité Paris-Saclay, INRAE, MICALIS Institute, Jouy-en-Josas, France.
Cassandre Bedu-Ferrari *Université Paris-Saclay, INRAE, MICALIS Institute, Jouy-en-Josas, France.
Lucie Etienne-Mesmin *Université Clermont Auvergne, INRAE, UMR 454 MEDIS, Clermont-Ferrand, France.
Mahendra MariadassouUniversité Paris-Saclay, INRAE, MaIAGE, Jouy-en-Josas, France.
Lucie LebreuillyUniversité Paris-Saclay, INRAE, MICALIS Institute, Jouy-en-Josas, France.
Seav-Ly TranUniversité Paris-Saclay, INRAE, MICALIS Institute, Jouy-en-Josas, France.
Laurence BrazeauUniversité Paris-Saclay, INRAE, MICALIS Institute, Jouy-en-Josas, France.
Camille MayeurUniversité Paris-Saclay, INRAE, MICALIS Institute, Jouy-en-Josas, France.
Julien DelmasUniversité Clermont Auvergne, Inserm U1071, M2iSH, USC-INRA 2018, Clermont-Ferrand, France.
Olivier RuéUniversité Paris-Saclay, INRAE, MaIAGE, Jouy-en-Josas, France.
Sylvain DenisUniversité Clermont Auvergne, INRAE, UMR 454 MEDIS, Clermont-Ferrand, France.
Stéphanie Blanquet-DiotUniversité Clermont Auvergne, INRAE, UMR 454 MEDIS, Clermont-Ferrand, France.
Nalini RamaraoUniversité Paris-Saclay, INRAE, MICALIS Institute, Jouy-en-Josas, France.
Université Paris-Saclay · FRUniversité Clermont Auvergne · FRInserm · FR

Funding

Institut National de la Recherche Agronomique (INRA) MICA-MEM
6 · The paper itself

Abstract

The disruption of gut microbiota homeostasis has been associated with numerous diseases and with a disproportionate inflammatory response, including overproduction of nitric oxide (NO) in the intestinal lumen. However, the influence of NO on the human gut microbiota has not been well characterized yet. We used

Indexed as

anaerobic digesterdiversityfunctional analysismetabolomicsmicrobiotanitric oxidesingle strain

Identifiers

PMID34519530
PMCPMC8547463
OpenAlexW3200478667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.