ArticleAsia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists2022
Analysis of the trends of polypharmacy and high-dose prescriptions in Japan.
Article in Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 12 citations in OpenAlex.
- Impact of community pharmacists on improving polypharmacy in elderly outpatients: a community-based intervention study.Journal of pharmaceutical health care and sciences · 2026Article
- Understanding Undergraduate Medicines Optimisation Education and Its Importance; a Realist Evaluation.Perspectives on medical education · 2026Article
- Psychosocial characteristics of the general population who habitually use hypnotics: Results from a national survey on drug use among the Japanese.PCN reports : psychiatry and clinical neurosciences · 2024Article
- Alcohol and toxicological factors influencing fatal falls from height in the Greater Tokyo Area: a retrospective study.International journal of legal medicine · 2024Article
- Effect of education regarding treatment guidelines for schizophrenia and depression on the treatment behavior of psychiatrists: A multicenter study.Psychiatry and clinical neurosciences · 2023Article
- Sodium Valproate Use in Japanese Patients with Schizophrenia and Coronavirus Disease Is Associated with an Increased Risk of Pneumonia.Journal of clinical medicine · 2023Article
- A Comparison between Perceptions of Psychiatric Outpatients and Psychiatrists Regarding Benzodiazepine Use and Decision Making for Its Discontinuation: A Cross-Sectional Survey in Japan.International journal of environmental research and public health · 2023Article
- Regional difference in multi-psychotropic drug prescription in Japan and its associated factors: an ecological study using national health insurance claims data.Research in health services & regions · 2023Article
- Analysis of the trends of polypharmacy and high-dose prescriptions in Japan.Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists · 2022Article
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Abstract
introductionAfter extensive research, this study explored whether high-dose prescriptions and polypharmacy remain more frequent in Japan than elsewhere. If confirmed, we aimed to identify the factors that contributed to this unique trend.
methodsThe psychotropic drug prescription patterns for patients with schizophrenia in Japan were reviewed. This was based on a large sample collected from surveys of the Research on Asian Psychotropic Prescription Patterns, an international collaborative research project conducted by Asian psychiatrists to monitor prescriptions of psychotropic drugs for people with mental disorders, in 2001, 2004, 2008, and 2016.
resultsThe 2016 Research on Asian Psychotropic Prescription Patterns survey revealed that Japan continued to demonstrate the highest rate of polypharmacy and the highest dosages of psychotropic prescription drugs for patients with schizophrenia among the 15 countries and areas that participated in the survey. DISCUSSION: The Research on Asian Psychotropic Prescription Patterns surveys demonstrated that science plays a limited role in the decision-making process for prescriptions of psychotropic medications. Such prescriptions are influenced by a wide range of factors, such as the national mental health policy, prescription-financing systems, the history of psychiatry in each country, and the prevailing culture. Hospital-based national mental health policies and mental health financing systems have been the primary obstacles to reducing polypharmacy in Japan.
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