Evidence map›Paper›PMID 34519364›Full record

ArticleMedical physics2021

Intraoperative cone-beam and slot-beam CT: 3D image quality and dose with a slot collimator on the O-arm imaging system.

Xiaoxuan Zhang, Wojciech Zbijewski, Yixuan Huang, Ali Uneri, Craig K Jones, Sheng-Fu L Lo, Timothy F Witham, Mark Luciano, William Stanley Anderson, Patrick A Helm and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Xiaoxuan ZhangDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
Wojciech ZbijewskiDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
Yixuan HuangDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
Ali UneriDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
Craig K JonesThe Malone Center for Engineering in Healthcare, Johns Hopkins University, Baltimore, Maryland, USA.
Sheng-Fu L LoDepartment of Neurosurgery, Johns Hopkins Medical Institute, Baltimore, Maryland, USA.
Timothy F WithamDepartment of Neurosurgery, Johns Hopkins Medical Institute, Baltimore, Maryland, USA.
Mark LucianoDepartment of Neurosurgery, Johns Hopkins Medical Institute, Baltimore, Maryland, USA.
William Stanley AndersonDepartment of Neurosurgery, Johns Hopkins Medical Institute, Baltimore, Maryland, USA.
Patrick A HelmMedtronic Inc., Littleton, Massachusetts, USA.
Jeffrey H SiewerdsenDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
Johns Hopkins University · USJohns Hopkins Bayview Medical Center · USMedtronic (United States) · US

Funding

Imaging, Guidance, and QA for Emerging High-Precision Neurosurgical TechniquesU01NS107133 · NINDS · JOHNS HOPKINS UNIVERSITY · PI SIEWERDSEN, JEFFREY H, UNERI, ALI · 2019 to 2023
$3.3M
Biomedical Research Partnership with Medtronic (Littleton MA)NIH HHS U01-NS-107133NINDS NIH HHS U01 NS107133
6 · The paper itself

Abstract

purposeTo characterize the 3D imaging performance and radiation dose for a prototype slot-beam configuration on an intraoperative O-arm™ Surgical Imaging System (Medtronic Inc., Littleton, MA) and identify potential improvements in soft-tissue image quality for surgical interventions.

methodsA slot collimator was integrated with the O-arm

resultsThe dose for a slot-beam scan varied from 0.02-0.06 mGy/mAs for head protocols to 0.01-0.03 mGy/mAs for body protocols, yielding dose reduction by ∼1/5 to 1/3 compared to cone-beam, owing to beam collimation and reduced x-ray scatter. The slot-beam provided an ∼6-7× reduction in scatter-to-primary ratio (SPR) compared to the cone-beam, yielding SPR ∼20-80% for head and body without the grid and ∼7-30% with the grid. Compared to cone-beam scans at equivalent dose, slot-beam images exhibited an ∼2.5× increase in soft-tissue contrast-to-noise ratio (CNR) for both grid and gridless configurations. For slot-beam scans, a further ∼10-30% improvement in CNR was achieved when the grid was removed. Slot-beam imaging could benefit certain interventional scenarios in which improved visualization of soft tissues is required within a fairly narrow longitudinal region of interest (

conclusionsThe 3D imaging performance and dose of a prototype slot-beam CT configuration on the O-arm

Indexed as

Imaging, Three-DimensionalSurgery, Computer-AssistedCone-Beam Computed TomographyPhantoms, ImagingScattering, RadiationTomography, X-Ray Computedcone-beam CTfan-beam CTimage-guided surgeryimage qualityintraoperative imagingradiation dosex-ray scatter

Identifiers

PMID34519364
PMCPMC10174643
OpenAlexW3201526998

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.