ArticleEnvironmental science & technology2021
Addressing Urgent Questions for PFAS in the 21st Century.
Article in Environmental science & technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 160 citations in OpenAlex.
- A Legacy of Exposure: Lactational PFAS Transfer and Early-Life Accumulation in Northern Elephant Seals.Environment & health (Washington, D.C.) · 2026Article
- When pathways trump orbitals in electrolyte design.Nature chemistry · 2026Article
- Photothermal Degradation of Pollutants Using a Ag@ZnNP/TiOChemPlusChem · 2026Article
- Is drinking water with low PFAS a significant source of human exposure? Evidence summary.Journal of exposure science & environmental epidemiology · 2026Review
- Article
- An Ecosystem-Scale Model of PFAS Dynamics in Stream-to-Riparian Food Webs.Environmental science & technology · 2026Article
- Per- and Polyfluoroalkyl Substances Leaching from Micro- and Nanoplastics and the Associated Influence of the Plastisphere.Environmental science & technology · 2026Article
- Water-Induced Confinement of Perfluorinated Pollutants in Biobased Polyamide Nanofibrous Membranes.ACS applied materials & interfaces · 2026Article
- Non-targeted screening of per- and polyfluoroalkyl substances: Advanced methods, challenges, and environmental health.Eco-Environment & Health · 2026Review
- Effects of an information shock on registry-based health indicators: Evidence from a Swedish PFAS crisis.PloS one · 2026Article
- Evaluation and comparison of tools used to quantify aggregate PFAS exposure: Extractable organic fluorine, PFAS burden scores and summed PFAS concentrations.Journal of exposure science & environmental epidemiology · 2025Article
- Article
- Unraveling the Adsorptive/Catalytic Roles of Carbonaceous Materials in Per- and Polyfluoroalkyl Substance (PFAS) Degradation: Current Status and Perspectives.Environmental science & technology · 2025Review
- Assessing AlphaFold 3 for Per- and Polyfluoroalkyl Substances Docking in Protein Structures.Environmental science & technology · 2025Article
- A Comprehensive, Simple, Robust, and Solvent-Free Method Covering Ultrashort- to Long-Chain PFAS in Atmospheric Samples.Analytical chemistry · 2025Article
- High-resolution mass spectrometry for extended PFAS surveillance in food: combining suspect and non-targeted approaches.Food chemistry: X · 2025Article
- Systems approaches in public health: beyond mapping the causes.The international journal of behavioral nutrition and physical activity · 2025Review
- Towards a Better Understanding of the Human Health Risk of Per- and Polyfluoroalkyl Substances Using Organoid Models.Bioengineering (Basel, Switzerland) · 2025Article
- Associations between per- and polyfluoroalkyl chemicals and abdominal aortic calcification in middle-aged and older adults.Journal of advanced research · 2025Article
- Research Progress in Current and Emerging Issues of PFASs' Global Impact: Long-Term Health Effects and Governance of Food Systems.Foods (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 11 institutions in 7 countries.
Funding
Abstract
Despite decades of research on per- and polyfluoroalkyl substances (PFAS), fundamental obstacles remain to addressing worldwide contamination by these chemicals and their associated impacts on environmental quality and health. Here, we propose six urgent questions relevant to science, technology, and policy that must be tackled to address the "PFAS problem": (1) What are the global production volumes of PFAS, and where are PFAS used? (2) Where are the unknown PFAS hotspots in the environment? (3) How can we make measuring PFAS globally accessible? (4) How can we safely manage PFAS-containing waste? (5) How do we understand and describe the health effects of PFAS exposure? (6) Who pays the costs of PFAS contamination? The importance of each question and barriers to progress are briefly described, and several potential paths forward are proposed. Given the diversity of PFAS and their uses, the extreme persistence of most PFAS, the striking ongoing lack of fundamental information, and the inequity of the health and environmental impacts from PFAS contamination, there is a need for scientific and regulatory communities to work together, with cooperation from PFAS-related industries, to fill in critical data gaps and protect human health and the environment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.