Evidence map›Paper›PMID 34519197›Full record

ArticleBiochemistry2021

Partial Opening of Cytochrome P450cam (CYP101A1) Is Driven by Allostery and Putidaredoxin Binding.

Simon P Skinner, Alec H Follmer, Marcellus Ubbink, Thomas L Poulos, Jeanine J Houwing-Duistermaat, Emanuele Paci

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Simon P SkinnerSchool of Molecular and Cell Biology and Astbury Centre, University of Leeds, Leeds LS2 9JT, U.K.
Alec H FollmerDepartment of Chemistry, University of California, Irvine, California 92697-3900, United States.
Marcellus UbbinkLeiden University, Institute of Chemistry, Einsteinweg 55, 2333 CC Leiden, The Netherlands.ORCID 0000-0002-2615-6914
Thomas L PoulosDepartment of Chemistry, University of California, Irvine, California 92697-3900, United States.ORCID 0000-0002-5648-3510
Jeanine J Houwing-DuistermaatSchool of Mathematics, University of Leeds, Leeds LS2 9JT, U.K.
Emanuele PaciSchool of Molecular and Cell Biology and Astbury Centre, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0000-0002-4891-2768
University of Leeds · GBUniversity of California, Irvine · USLeiden University · NL

Funding

Metalloenzyme structure, function, and as targets for neurodegeneration and bacterial pathogenesisR35GM131920 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI POULOS, THOMAS L · 2019 to 2023
$2.9M
NIGMS NIH HHS R35 GM131920
6 · The paper itself

Abstract

Cytochrome P450cam (CYP101A1) catalyzes the regio- and stereo-specific 5-

Indexed as

Allosteric RegulationBacterial ProteinsCamphorCamphor 5-MonooxygenaseCatalytic DomainCrystallography, X-RayFerredoxinsMagnetic Resonance SpectroscopyModels, MolecularProtein BindingProtein ConformationPseudomonas putidaBacterial ProteinsCamphorCamphor 5-MonooxygenaseFerredoxinsputidaredoxin

Identifiers

PMID34519197
PMCPMC8959389
OpenAlexW3201601633

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.