ArticleScientific reports2021
Lactobacillus crispatus thrives in pregnancy hormonal milieu in a Nigerian patient cohort.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Influence of Hormonal Contraceptive Use and HIV on Cervicovaginal Cytokines and Microbiota in Malawi.mSphere · 2023Trial
- Vaginal microbiomes and their pertinent social context: a microbial ecological review proffering AMR-STI acquisition and emergence.Biology of sex differences · 2026Review
- Lactobacillus iners at the nexus of microbiota, immunity, and pregnancy.Journal of reproductive immunology · 2026Review
- Microbial Contributions to Primate Reproduction.Evolutionary anthropology · 2026Review
- The vaginal bacteriome of pregnant Rwandan and Kenyan women, unique regional genera associations with preterm birth.BMC microbiology · 2026Article
- Factors shaping vaginal microbiota long-term community dynamics in young adult women.Peer community journal · 2025Article
- A rigorous and versatile statistical test for correlations between stationary time series.PLoS biology · 2024Article
- Article
- Observational
- The Vaginal Microbiota of Pregnant Women Varies with Gestational Age, Maternal Age, and Parity.Microbiology spectrum · 2023Article
- Longitudinal Course of Sex Steroids From Pregnancy to Postpartum.Endocrinology · 2023Review
- The Bacterial DNA Profiling of Chorionic Villi and Amniotic Fluids Reveals Overlaps with Maternal Oral, Vaginal, and Gut Microbiomes.International journal of molecular sciences · 2023Article
- Microbiota dynamics, metabolic and immune interactions in the cervicovaginal environment and their role in spontaneous preterm birth.Frontiers in immunology · 2023Review
- Parity and gestational age are associated with vaginal microbiota composition in term and late term pregnancies.EBioMedicine · 2022Article
- Role of short interpregnancy interval, birth mode, birth practices, and the postpartum vaginal microbiome in preterm birth.Frontiers in reproductive health · 2022Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Steroid hormones are one of the presumed modulators of Lactobacillus abundance in the vaginal epithelium. We set out to characterize the vaginal microbiome (VMB) and also provide an in-depth understanding of the relative contribution of estradiol (E2) and progesterone (P1) in shaping the vaginal microbiome of Nigerian women (n = 38) who experienced both uncomplicated term delivery and preterm delivery using samples longitudinally collected during pregnancy (17-21, 27-31, 36-41 weeks gestation) and 6 weeks postpartum. Vaginal swabs and blood samples were aseptically collected. Vaginal swabs were used for microbiome assessment using 16S ribosomal RNA (rRNA) gene sequencing. Blood samples were used for hormonal measurement using a competitive-based enzyme-linked immunosorbent assay (ELISA). Across several maternal covariates, maternal age, pregnancy status and delivery mode were not significantly associated with the vaginal microbiota whereas maternal E2 level (p
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