ArticleDiabetes care2022
Minimum Threshold of Bariatric Surgical Weight Loss for Initial Diabetes Remission.
Article in Diabetes care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 46 citations in OpenAlex.
- Weight loss and β-cell responses following gastric banding or pharmacotherapy in adults with impaired glucose tolerance or type 2 diabetes: a randomized trial.Obesity (Silver Spring, Md.) · 2022Trial
- Weight Loss Threshold and Inflection Points for Biochemical Remission of Male Obesity-Associated Secondary Hypogonadism After Sleeve Gastrectomy.Obesity surgery · 2026Article
- Single-Anastomosis Duodenoileal Bypass Conversion for Sleeve Gastrectomy: Three-Year Outcomes Comparing 300 cm vs 250 cm Common Channel Length.Obesity surgery · 2026Article
- Clinical and Metabolic Characteristics of Spontaneous Remission in Type 2 Diabetes: A Real-World Study from South India.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026Article
- Determinants of Diabetes Remission and Relapse following Sleeve Gastrectomy and Gastric Bypass: A 2- and 5-Year Follow-Up Study.Obesity facts · 2026Article
- Is All Weight Loss Equal Following Sleeve Gastrectomy? Defining Body Composition and Anthropometric Thresholds for Hyperglycemia Remission in Women from a Prospective Cohort Study.Obesity surgery · 2026Article
- Bariatric Surgery in the Era of GLP1RA: A Narrative Review.Advances in therapy · 2026Review
- Long-Limb Roux-en-Y Reconstruction for Glycemic Control in Patients with Gastric Cancer and Type 2 Diabetes: One-Year Outcomes of Oncometabolic Surgery.Digestive surgery · 2026Article
- Gut microbiota alterations induced by Roux-en-Y gastric bypass result in glucose-lowering by enhancing intestinal glucose excretion.Gut microbes · 2025Article
- Discrimination of myelofibrosis and liver cirrhosis using a spleen ultrasound-based radiomics nomogram model.Experimental and therapeutic medicine · 2025Article
- Experiences and Perspectives of Racially Diverse Patients 5 Years Post-Bariatric Surgery: Qualitative Findings from the BELONG II Study.Journal of racial and ethnic health disparities · 2025Article
- DiaBar: Predicting type 2 diabetes remission post-metabolic surgery utilizing mRNA expression profiles from subcutaneous adipose tissue.Journal of clinical & translational endocrinology · 2025Article
- A Nomogram for Prediction of Weight Loss Outcomes after Bariatric Surgery.Obesity surgery · 2025Article
- Type 2 Diabetes Mellitus Remission, Dream or Reality? A Narrative Review of Current Evidence and Integrated Care Strategies.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Review
- Binge eating behaviours are associated with recurrent weight gain after metabolic and bariatric surgery.Clinical obesity · 2025Article
- Optimizing Hospital Performance Evaluation in Total Weight Loss Outcomes After Bariatric Surgery: A Retrospective Analysis to Guide Further Improvement in Dutch Hospitals.Obesity surgery · 2024Article
- Pre-surgical factors related to latent trajectories of 5-year weight loss for a diverse bariatric surgery population.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2024Article
- Back to the future: malabsorption is the Achilles' heel of hypoabsorptive metabolic/bariatric procedures.The British journal of surgery · 2024Article
- Observational cohort investigating health outcomes and healthcare costs after metabolic and bariatric surgery: a study protocol.BMJ open · 2024Article
- Assessing the Efficacy of Extended Postoperative Enoxaparin as Thromboprophylaxis for Patients Undergoing Laparoscopic Sleeve Gastrectomy: a Prospective Analysis.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2024Article
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16 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveThere are few studies testing the amount of weight loss necessary to achieve initial remission of type 2 diabetes mellitus (T2DM) following bariatric surgery and no published studies with use of weight loss to predict initial T2DM remission in sleeve gastrectomy (SG) patients. RESEARCH DESIGN AND
methodsWith Cox proportional hazards models we examined the relationship between initial T2DM remission and percent total weight loss (%TWL) after bariatric surgery. Categories of %TWL were included in the model as time-varying covariates.
resultsOf patients (N = 5,928), 73% were female; mean age was 49.8 ± 10.3 years and BMI 43.8 ± 6.92 kg/m2, and 57% had Roux-en-Y gastric bypass (RYGB). Over an average follow-up of 5.9 years, 71% of patients experienced initial remission of T2DM (mean time to remission 1.0 year). With 0-5% TWL used as the reference group in Cox proportional hazards models, patients were more likely to remit with each 5% increase in TWL until 20% TWL (hazard ratio range 1.97-2.92). When categories >25% TWL were examined, all patients had a likelihood of initial remission similar to that of 20-25% TWL. Patients who achieved >20% TWL were more likely to achieve initial T2DM remission than patients with 0-5% TWL, even if they were using insulin at the time of surgery.
conclusionsWeight loss after bariatric surgery is strongly associated with initial T2DM remission; however, above a threshold of 20% TWL, rates of initial T2DM remission did not increase substantially. Achieving this threshold is also associated with initial remission even in patients who traditionally experience lower rates of remission, such as patients taking insulin.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.