Evidence map›Paper›PMID 34518374›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

High frequency of an otherwise rare phenotype in a small and isolated tiger population.

Vinay Sagar, Christopher B Kaelin, Meghana Natesh, P Anuradha Reddy, Rajesh K Mohapatra, Himanshu Chhattani, Prachi Thatte, Srinivas Vaidyanathan, Suvankar Biswas, Supriya Bhatt and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The year of the tiger and the year of tiger genomes!Molecular ecology resources · 2023
    Article
  7. Article
  8. Review
  9. Genomic evidence for inbreeding depression and purging of deleterious genetic variation in Indian tigers.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Broad tiger stripes in a small habitat patch.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 2 countries.

Vinay SagarNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore 560065, India; vinays@ncbs.res.in uramakri@ncbs.res.in.ORCID 0000-0001-7690-758X
Christopher B KaelinDepartment of Genetics, Stanford University, Palo Alto, CA 94309.
Meghana NateshNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore 560065, India.ORCID 0000-0002-6712-4214
P Anuradha ReddyLaboratory for Conservation of Endangered Species, Center for Cellular & Molecular Biology, Hyderabad 500048, India.ORCID 0000-0002-3808-7223
Rajesh K MohapatraNandankanan Biological Park, Bhubaneswar 754005, India.ORCID 0000-0002-4381-4421
Himanshu ChhattaniNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore 560065, India.
Prachi ThatteWorld Wide Fund for Nature - India, New Delhi 110003 India.
Srinivas VaidyanathanFoundation for Ecological Research, Advocacy and Learning, Auroville Post, Tamil Nadu 605101 India.ORCID 0000-0003-3642-0309
Suvankar BiswasWildlife Institute of India, Dehradun 248001, India.ORCID 0000-0003-3814-6905
Supriya BhattWildlife Institute of India, Dehradun 248001, India.ORCID 0000-0003-2308-959X
Shashi PaulOdisha Forest Department, Bhubaneswar 751023, India.
Yadavendradev V JhalaWildlife Institute of India, Dehradun 248001, India.ORCID 0000-0003-3276-1384
Mayank M VermaState Forest Research Institute, Jabalpur 482008, India.
Bivash PandavWildlife Institute of India, Dehradun 248001, India.
Samrat MondolWildlife Institute of India, Dehradun 248001, India.ORCID 0000-0003-3034-9396
Gregory S BarshDepartment of Genetics, Stanford University, Palo Alto, CA 94309.
Debabrata SwainFormer Member Secretary, National Tiger Conservation Authority, New Delhi 110003, India.
Uma RamakrishnanNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore 560065, India; vinays@ncbs.res.in uramakri@ncbs.res.in.ORCID 0000-0002-5370-5966
Wildlife Institute of India · INTata Institute of Fundamental Research · INPalo Alto University · USCentre for Cellular and Molecular Biology · INDelhi Development Authority · INTropical Forest Research Institute · INWWF-India · IN

Funding

DBT-Wellcome Trust India Alliance IA/S/16/2/502714Wellcome Trust
6 · The paper itself

Abstract

Most endangered species exist today in small populations, many of which are isolated. Evolution in such populations is largely governed by genetic drift. Empirical evidence for drift affecting striking phenotypes based on substantial genetic data are rare. Approximately 37% of tigers (

Indexed as

Biological EvolutionGenetic DriftGenetics, PopulationGenetic VariationPhenotypeAmino Acid SequenceAnimalsConservation of Natural ResourcesEndangered SpeciesGenomeGenotypeIndiaMelanosisMicrosatellite RepeatsSequence HomologyTigersdriftgeneticsinbreedingpseudomelanismselection

Identifiers

PMID34518374
PMCPMC8488692
OpenAlexW3201045580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.