Evidence map›Paper›PMID 34517941›Full record

ArticleeLife2021

Translational control of polyamine metabolism by CNBP is required for

Sonia Coni, Federica A Falconio, Marta Marzullo, Marzia Munafò, Benedetta Zuliani, Federica Mosti, Alessandro Fatica, Zaira Ianniello, Rosa Bordone, Alberto Macone and 7 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  4. ThebioRxiv : the preprint server for biology · 2025
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  7. International journal of molecular sciences · 2025
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  8. Decoding Nucleotide Repeat Expansion Diseases: Novel Insights fromInternational journal of molecular sciences · 2024
    Review
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  11. Neto proteins differentially modulate the gating properties ofbioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Modeling Myotonic Dystrophy Type 2 UsingInternational journal of molecular sciences · 2023
    Review
  14. Review
  15. Review
  16. Ornithine decarboxylase deficiency critically impairs nitrogen metabolism and survival in Aedes aegypti mosquitoes.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 4 countries.

Sonia Coni *Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-0295-8904
Federica A Falconio *Department of Biology and Biotechnologies, Sapienza University of Rome, Rome, Italy.
Marta Marzullo *Department of Biology and Biotechnologies, Sapienza University of Rome, Rome, Italy.ORCID 0000-0001-7229-1693
Marzia MunafòEuropean Molecular Biology Laboratory (EMBL) Epigenetics & Neurobiology Unit, Campus Adriano Buzzati-Traverso, Monterotond, Italy.ORCID 0000-0002-2689-8432
Benedetta ZulianiDepartment of Biology and Biotechnologies, Sapienza University of Rome, Rome, Italy.
Federica MostiDepartment of Biology and Biotechnologies, Sapienza University of Rome, Rome, Italy.
Alessandro FaticaDepartment of Biology and Biotechnologies, Sapienza University of Rome, Rome, Italy.
Zaira IannielloDepartment of Biology and Biotechnologies, Sapienza University of Rome, Rome, Italy.
Rosa BordoneDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Alberto MaconeDepartment of Biochemical Sciences, Sapienza University of Rome, Rome, Italy.
Enzo AgostinelliDepartment of Sensory Organs, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy.
Alessia PernaDepartment of Neuroscience, Fondazione Policlinico Gemelli IRCCS, University Cattolica del S. Cuore, Roma, Italy.
Tanja MatkovicFreie Universität Berlin, Institute for Biology and Genetics, Berlin, Germany.
Stephan SigristFreie Universität Berlin, Institute for Biology and Genetics, Berlin, Germany.ORCID 0000-0002-1698-5815
Gabriella SilvestriDepartment of Neuroscience, Fondazione Policlinico Gemelli IRCCS, University Cattolica del S. Cuore, Roma, Italy.
Gianluca CanettieriDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.ORCID 0000-0001-6694-2613
Laura CiapponiDepartment of Biology and Biotechnologies, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-0817-1862
Sapienza University of Rome · ITFreie Universität Berlin · DEAgostino Gemelli University Polyclinic · ITDuke University · USEuropean Molecular Biology Laboratory · ITImperial College London · GBInstitute of Molecular Biology and Pathology · ITIstituto Pasteur · ITPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microsatellite expansions of CCTG repeats in the cellular nucleic acid-binding protein (

Indexed as

AnimalsAnimals, Genetically ModifiedCell LineDown-RegulationDrosophila melanogasterDrosophila ProteinsGene Expression RegulationHEK293 CellsHumansMotor ActivityMuscle, SkeletalMyotonic DystrophyPolyaminesProtein BiosynthesisPutrescineRNA-Binding ProteinsCNBP protein, DrosophilaDrosophila ProteinsPolyaminesPutrescineRNA-Binding ProteinsSpermidineCNBPD. melanogasterDrosophila melanogastergeneticsgenomicshumanmyotonic dystrophy 2neuroscienceODCpolyaminetranslation

Identifiers

PMID34517941
PMCPMC8439652
OpenAlexW3201269128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.