Evidence map›Paper›PMID 34517820›Full record

ArticleBMC infectious diseases2021

Quality of life in people living with HIV in Romania and Spain.

Meaghan Kall, Ujué Fresán, Danielle Guy, Graham Brown, Cristina Burgui, Jesús Castilla, Victor Ionel Grecu, Florentina Dumitrescu, Valerie Delpech, Jeffrey V Lazarus

Abstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. An international compendium of health state utilities in people with HIV: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Pooled it
  2. Article
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  7. A Study on AIDS Self-Management Status and Its Influencing Factors.Journal of multidisciplinary healthcare · 2024
    Article
  8. Article
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  10. EQ-5D-5L: a value set for Romania.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Meaghan KallHIV/STI Department, Public Health England, London, NW9 5EQ, UK. Meaghan.Kall@phe.gov.uk.ORCID http://orcid.org/0000-0001-6971-427X
Ujué FresánInstituto de Salud Pública de Navarra-IdiSNA-CIBERESP, Pamplona, Spain.
Danielle GuyBarcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, S08036, Barcelona, Spain.
Graham BrownCentre for Social Impact, University of New South Wales, High Street, Sydney, Australia.
Cristina BurguiInstituto de Salud Pública de Navarra-IdiSNA-CIBERESP, Pamplona, Spain.
Jesús CastillaInstituto de Salud Pública de Navarra-IdiSNA-CIBERESP, Pamplona, Spain.
Victor Ionel GrecuSpitalul Clinic de Boli Infectioase si Pneumoftiziologie "Victor Babes" Craiova, 200515, Craiova, Romania.
Florentina DumitrescuSpitalul Clinic de Boli Infectioase si Pneumoftiziologie "Victor Babes" Craiova, 200515, Craiova, Romania.
Valerie DelpechHIV/STI Department, Public Health England, London, NW9 5EQ, UK.
Jeffrey V LazarusBarcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, S08036, Barcelona, Spain.

Funding

Executive Agency for Health and Consumers 761319
6 · The paper itself

Abstract

backgroundHealth-related quality of life (HRQoL) is a crucial component in assessing and addressing the unmet needs of people, especially those with chronic illnesses such as HIV. The aim of the study was to examine and compare the health-related quality of life of people living with HIV in Romania and Spain, compared to the general populations of each country.

methodsA cross-sectional survey was conducted among adults (≥ 18 years) attending for HIV care in Romania and Spain from October 2019 to March 2020. The survey included two validated HRQoL instruments: a generic instrument, EQ-5D-5L, and an HIV-specific instrument, PozQoL, and questions on socio-demographics, HIV-related characteristics, physical and mental health conditions, and substance use. Multivariable linear regression was used to determine factors associated with HRQoL.

results570 people living with HIV responded (170 in Romania and 400 in Spain). The median age was 31 (18-67) in Romania and 52 (19-83) in Spain. Anxiety/depression symptoms were frequently reported by people with HIV (Romania: 50% vs 30% in the Romanian population; Spain: 38% vs 15% in Spanish population). Spain reported higher mean EQ-5D

conclusionsOur results indicated a good HRQoL for people living with HIV in Romania and Spain; however, worse HRQoL profiles were characterized by health concerns, poor self-rated health status, and the presence of mental health conditions. This study highlights the importance of monitoring HRQoL in people living with HIV due to the chronic nature of the disease. In this highly-treatment experienced group, disparities were found, particularly highlighting mental health as an area which needs more attention to improve the well-being of people living with HIV.

Indexed as

HIV InfectionsQuality of LifeAdultAgedCross-Sectional StudiesHumansRomaniaSpainChronic diseasesEQ-5DHealth-related quality of lifeHIV/AIDSPozQoLRomaniaSpain

Identifiers

PMID34517820
PMCPMC8436864

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.