ArticleStroke2022
Temporal Profile of Pneumonia After Stroke.
Article in Stroke, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 44 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- European stroke organisation guideline on stroke-associated pneumonia.European stroke journal · 2026Guideline
- CHOSEN: A Randomized Controlled Feasibility Trial.Journal of the American Heart Association · 2025Trial
- Metoclopramide to Prevent Pneumonia in Patients With Stroke and a Nasogastric Tube: Data From the PRECIOUS Trial.Stroke · 2024Trial
- Advances in stroke-associated pneumonia in the era of revascularization therapy.Chinese medical journal · 2026Review
- Development and external validation of a risk stratification model for stroke-associated pneumonia.iScience · 2026Article
- Hospital-Course Infectious Complications Associated with In-Hospital Mortality in a Neurological Intensive Care Cohort: A Six-Year Retrospective Study.Journal of clinical medicine · 2026Article
- Extracellular Vesicles in Stroke: Drivers of Brain-Body Network Crosstalk.Translational stroke research · 2026Review
- Correlation between swallowing and diaphragmatic functions in stroke patients with hemiplegia: a cross-sectional observational study.Scientific reports · 2026Observational
- Relationship Between Prognostic Nutritional Index and Stroke-Associated Pneumonia in Elderly Patients: A Two-Center Study of Spontaneous Intracerebral Hemorrhage.Food science & nutrition · 2026Article
- Article
- Low hemoglobin-albumin-lymphocyte-platelet score as a risk marker for stroke-associated pneumonia in acute ischemic stroke: a retrospective cohort study.Frontiers in neurology · 2026Article
- Temporal Profile of Stroke-Associated Pneumonia and Deep Vein Thrombosis after Stroke.Cerebrovascular diseases extra · 2026Article
- Catastrophic consequences of prolonged immobilization after intracerebral hemorrhage: a case report of crush syndrome combined with capillary leak syndrome.Frontiers in neuroscience · 2026Article
- Association between acute-phase glycaemic metrics and stroke-associated pneumonia in patients with acute ischaemic stroke.BMJ neurology open · 2026Article
- Gut dysbiosis, metabolic signals, and pulmonary immune reprogramming: decoding the gut microbiota -immune axis in stroke-associated pneumonia.Frontiers in immunology · 2026Review
- Stroke-associated pneumonia in Japanese acute care settings: incidence and preliminary validation of risk prediction scores.BMC neurology · 2025Article
- The impact of post-stroke pneumonia on survival and functional outcomes: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2025Review
- Dysphagia Management is Associated with Reduced Mortality in Patients with Moderate to Severe Acute Ischemic Stroke.Neurology and therapy · 2025Article
- Article
- Association of follow-up neutrophil-lymphocyte ratio with postoperative pneumonia in aneurysmal subarachnoid hemorrhage patients after endovascular treatment: a retrospective analysis.Frontiers in medicine · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe occurrence of pneumonia after stroke is associated with a higher risk of poor outcome or death. We assessed the temporal profile of pneumonia after stroke and its association with poor outcome at several time points to identify the most optimal period for testing pneumonia prevention strategies.
methodsWe analyzed individual patient data stored in the VISTA (Virtual International Stroke Trials Archive) from randomized acute stroke trials with an inclusion window up to 24 hours after stroke onset and assessed the occurrence of pneumonia in the first 90 days after stroke. Adjusted odds ratios and hazard ratios were calculated for the association between pneumonia and poor outcome and death by means of logistic and Cox proportional hazard regression, respectively, at different times of follow-up.
resultsOf 10 821 patients, 1017 (9.4%) had a total of 1076 pneumonias. Six hundred eighty-nine (64.0%) pneumonias occurred in the first week after stroke. The peak incidence was on the third day and the median time of onset was 4.0 days after stroke (interquartile range, 2-12). The presence of a pneumonia was associated with an increased risk of poor outcome (adjusted odds ratio, 4.8 [95% CI, 3.8-6.1]) or death (adjusted hazard ratio, 4.1 [95% CI, 3.7-4.6]). These associations were present throughout the 90 days of follow-up.
conclusionsTwo out of 3 pneumonias in the first 3 months after stroke occur in the first week, with a peak incidence on the third day. The most optimal period to assess pneumonia prevention strategies is the first 4 days after stroke. However, pneumonia occurring later was also associated with poor functional outcome or death.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.