Evidence map›Paper›PMID 34517753›Full record

ArticlemBio2021

Bacteroidetocins Target the Essential Outer Membrane Protein BamA of

Leigh M Matano, Michael J Coyne, Leonor García-Bayona, Laurie E Comstock

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. AmicroLife · 2026
    Article
  3. Review
  4. A nonenzymatic effector disruptsProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Life (Basel, Switzerland) · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Leigh M MatanoDivision of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Michael J CoyneDivision of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Leonor García-BayonaDivision of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-3176-4225
Laurie E ComstockDivision of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Brigham and Women's Hospital · US

Funding

STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI JONATHAN C KAGAN · 1986 to 2026
$32.4M
INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
Secreted antimicrobial proteins of the intestinal BacteriodalesR01AI093771 · NIAID · UNIVERSITY OF CHICAGO · PI LAURIE E COMSTOCK · 2012 to 2026
$5.1M
A new paradigm of respiration in the human gut BacteroidesR01AI132580 · NIAID · RENSSELAER POLYTECHNIC INSTITUTE · PI BARQUERA, BLANCA, COMSTOCK, LAURIE E · 2017 to 2020
$2.4M
NIAID NIH HHS R01 AI093771NIAID NIH HHS R01 AI132580NIAID NIH HHS T32 AI007061NIDDK NIH HHS P30 DK034854
6 · The paper itself

Abstract

Bacteroidetocins are a family of antibacterial peptide toxins that are produced by and target members of the phylum

Indexed as

Amino Acid MotifsAmino Acid SequenceAnimalsAnti-Bacterial AgentsBacterial Outer MembraneBacterial Outer Membrane ProteinsBacteriocinsBacteroidetesDrug Resistance, BacterialFemaleGastrointestinal MicrobiomeGastrointestinal TractGram-Negative Bacterial InfectionsHumansMiceSequence AlignmentAnti-Bacterial AgentsBacterial Outer Membrane ProteinsBacteriocinsbacteriocinBacteroidesBamAmicrobiota

Identifiers

PMID34517753
PMCPMC8546649
OpenAlexW3200915488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.