ArticleCirculation research2021
NLRP3 Inflammasome Mediates Immune-Stromal Interactions in Vasculitis.
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Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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56citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
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Who cites it
56 citing papers in PubMed, 74 citations in OpenAlex.
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- Sirtuin 1 Activation Mitigates Murine Vasculitis Severity by Promoting Autophagy and Mitophagy.bioRxiv : the preprint server for biology · 2025Article
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- Intestinal Microbiota Contributes to the Development of Cardiovascular Inflammation and Vasculitis in Mice.Circulation research · 2025Article
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- The role of the ER stress sensor IRE1 in cardiovascular diseases.Molecular and cellular biochemistry · 2025Review
- Involvement of USP7 in aggravating Kawasaki disease by promoting TGFβ2 signaling mediated endothelial-mesenchymal transition and coronary artery remodeling.International immunopharmacology · 2025Article
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Corrections and comments
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Authors and funding
15 authors at 3 institutions in 2 countries.
Rebecca A Porritt *Department of Pediatrics, Division of Infectious Diseases and Immunology, Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center (IIDRC) (R.A.P., M.A., Y.L., M.N., T.T.d.C., A.C.G., D.M., S.C., T.R.C., K.S., M.A., M.N.R.), Cedars-Sinai Medical Center, Los Angeles, CA.ORCID 0000-0002-0973-5092
David Zemmour *Department of Pathology, Harvard Medical School and Brigham and Women's Hospital, Boston, MA (D.Z.).ORCID 0000-0002-0990-217X
Masanori Abe *Department of Pediatrics, Division of Infectious Diseases and Immunology, Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center (IIDRC) (R.A.P., M.A., Y.L., M.N., T.T.d.C., A.C.G., D.M., S.C., T.R.C., K.S., M.A., M.N.R.), Cedars-Sinai Medical Center, Los Angeles, CA.ORCID 0000-0002-5641-4996
Youngho LeeDepartment of Pediatrics, Division of Infectious Diseases and Immunology, Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center (IIDRC) (R.A.P., M.A., Y.L., M.N., T.T.d.C., A.C.G., D.M., S.C., T.R.C., K.S., M.A., M.N.R.), Cedars-Sinai Medical Center, Los Angeles, CA.ORCID 0000-0002-5227-683X
Meena NarayananDepartment of Pediatrics, Division of Infectious Diseases and Immunology, Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center (IIDRC) (R.A.P., M.A., Y.L., M.N., T.T.d.C., A.C.G., D.M., S.C., T.R.C., K.S., M.A., M.N.R.), Cedars-Sinai Medical Center, Los Angeles, CA.
Thacyana T CarvalhoDepartment of Pediatrics, Division of Infectious Diseases and Immunology, Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center (IIDRC) (R.A.P., M.A., Y.L., M.N., T.T.d.C., A.C.G., D.M., S.C., T.R.C., K.S., M.A., M.N.R.), Cedars-Sinai Medical Center, Los Angeles, CA.ORCID 0000-0002-8580-6200
Angela C GomezDepartment of Pediatrics, Division of Infectious Diseases and Immunology, Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center (IIDRC) (R.A.P., M.A., Y.L., M.N., T.T.d.C., A.C.G., D.M., S.C., T.R.C., K.S., M.A., M.N.R.), Cedars-Sinai Medical Center, Los Angeles, CA.
Daisy MartinonDepartment of Pediatrics, Division of Infectious Diseases and Immunology, Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center (IIDRC) (R.A.P., M.A., Y.L., M.N., T.T.d.C., A.C.G., D.M., S.C., T.R.C., K.S., M.A., M.N.R.), Cedars-Sinai Medical Center, Los Angeles, CA.
Chintda SantiskulvongDepartment of Pediatrics, Division of Infectious Diseases and Immunology, Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center (IIDRC) (R.A.P., M.A., Y.L., M.N., T.T.d.C., A.C.G., D.M., S.C., T.R.C., K.S., M.A., M.N.R.), Cedars-Sinai Medical Center, Los Angeles, CA.
Michael C FishbeinDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA (M.C.F.).ORCID 0000-0002-6591-6306
Shuang ChenORCID 0000-0002-2919-4967
Timothy R CrotherDepartment of Pediatrics, Division of Infectious Diseases and Immunology, Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center (IIDRC) (R.A.P., M.A., Y.L., M.N., T.T.d.C., A.C.G., D.M., S.C., T.R.C., K.S., M.A., M.N.R.), Cedars-Sinai Medical Center, Los Angeles, CA.ORCID 0000-0001-8465-6127
Kenichi ShimadaDepartment of Pediatrics, Division of Infectious Diseases and Immunology, Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center (IIDRC) (R.A.P., M.A., Y.L., M.N., T.T.d.C., A.C.G., D.M., S.C., T.R.C., K.S., M.A., M.N.R.), Cedars-Sinai Medical Center, Los Angeles, CA.
Moshe Arditi *Department of Pediatrics, Division of Infectious Diseases and Immunology, Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center (IIDRC) (R.A.P., M.A., Y.L., M.N., T.T.d.C., A.C.G., D.M., S.C., T.R.C., K.S., M.A., M.N.R.), Cedars-Sinai Medical Center, Los Angeles, CA.ORCID 0000-0001-9042-2909
Magali Noval Rivas *Department of Pediatrics, Division of Infectious Diseases and Immunology, Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center (IIDRC) (R.A.P., M.A., Y.L., M.N., T.T.d.C., A.C.G., D.M., S.C., T.R.C., K.S., M.A., M.N.R.), Cedars-Sinai Medical Center, Los Angeles, CA.ORCID 0000-0001-5570-8928
Cedars-Sinai Medical Center · USBrigham and Women's Hospital · USUniversity of California, Los Angeles · US
Funding
UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1MRole of IL-1 in Bacterial ligand-induced vasculitis and myocarditisR01AI072726 · NIAID · CEDARS-SINAI MEDICAL CENTER · PI ARDITI, MOSHE · 2008 to 2020
$4.5MRole of intestinal microbiome and gut permeability in the development of Kawasaki Disease vasculitisR01HL139766 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI Magali Noval Rivas · 2018 to 2026
$3.4MRole of neutrophils and eosinophils in bacterial ligand-induced vasculitisR01AI157274 · NIAID · CEDARS-SINAI MEDICAL CENTER · PI ARDITI, MOSHE, NOVAL RIVAS, MAGALI · 2020 to 2024
$3.2MTargeting the Sirt-1 pathway to modulate inflammation during murine Kawasaki Disease vasculitisR01HL159297 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI NOVAL RIVAS, MAGALI · 2021 to 2024
$1.7MNCATS NIH HHS UL1 TR001881NHLBI NIH HHS R01 HL139766NHLBI NIH HHS R01 HL159297NIAID NIH HHS R01 AI072726NIAID NIH HHS R01 AI157274
Abstract
[Figure: see text].
Indexed as
AnimalsBlood VesselsCells, CulturedDendritic CellsFibroblastsInterleukin-1betaMacrophagesMaleMiceMice, Inbred C57BLMucocutaneous Lymph Node SyndromeMuscle, Smooth, VascularMyocytes, Smooth MuscleNLR Family, Pyrin Domain-Containing 3 ProteinReceptors, Interleukin-1 Type IStromal CellsInterleukin-1betaNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseReceptors, Interleukin-1 Type Iinflammasomesinflammationinterleukin-1monocytessmooth muscle myocytesvasculitis
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.