ArticleUltrasonography (Seoul, Korea)2022
Assessment of thyroid-specific quality of life in patients with benign symptomatic thyroid nodules treated with radiofrequency or ethanol ablation: a prospective multicenter study.
Article in Ultrasonography (Seoul, Korea), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Quality of Life Following Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis.Thyroid : official journal of the American Thyroid Association · 2025Pooled it
- Efficacy of radiofrequency and laser thermal ablation in solving thyroid nodule-related symptoms and cosmetic concerns. A systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2022Pooled it
- Comparison of thyroid-specific quality of life after thermal ablation vs. thyroid lobectomy for benign thyroid nodules.BMC endocrine disorders · 2026Article
- Single-session radiofrequency ablation for the treatment of benign cystic thyroid nodules: A prospective study.PloS one · 2026Article
- Thermal Ablation as a Non-Surgical Alternative for Thyroid Nodules: A Review of Current Evidence.Medicina (Kaunas, Lithuania) · 2025Review
- Impact of Thyroid Arterial Embolization on Clinical and Biochemical Outcomes and Quality of Life in Patients with Nodular and Multinodular Goiter.Cardiovascular and interventional radiology · 2025Article
- Radiofrequency Ablation of Benign Thyroid Nodules: 10-Year Follow-Up Results From a Single Center.Korean journal of radiology · 2025Article
- Comparison of the effectiveness of ultrasound-guided radiofrequency ablation and conventional open thyroidectomy in the treatment of benign thyroid nodules.Pakistan journal of medical sciences · 2024Article
- A Multi-dimensional Data Mining-based Study on the Prescriptions Developed by Professor Xu Zhiyin in Treating Thyroid Nodules.Endocrine, metabolic & immune disorders drug targets · 2024Article
- Ethanol ablation of thyroid cysts in the young with a focus on efficacy and quality of life.European thyroid journal · 2023Article
- Radiofrequency ablation of benign thyroid nodules: the value of anterolateral hydrodissection.Ultrasonography (Seoul, Korea) · 2023Article
- 2022 Taiwan clinical multicenter expert consensus and recommendations for thyroid radiofrequency ablation.Ultrasonography (Seoul, Korea) · 2023Article
Corrections and comments
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeRadiofrequency ablation (RFA) and ethanol ablation (EA) are effective and safe for benign symptomatic thyroid nodules (BSTNs). However, relatively little is known about the effects of these procedures on patients' quality of life (QoL). This prospective, multicenter study evaluated the effects of RFA and EA on changes in thyroid-specific QoL in patients with BSTNs and assessed the volume reduction and safety of these procedures.
methodsEighty-six consecutive patients with 86 BSTNs were prospectively included from two medical centers. RFA was performed for 55 BSTNs with solidity ≥50% and EA was performed for 31 BSTNs with solidity <50%. QoL was evaluated using an 11-scale, multiple-choice thyroid-specific QoL questionnaire. Nodule characteristics and QoL were evaluated at diagnosis and 1, 6, and 12 months after treatment. Overall QoL was rated from 0 (good) to 4 (poor).
resultsThe mean longest size and volume of the index nodule were 4.2±1.5 cm and 21.6±22.1 mL, respectively. Patients received 1.1 treatments on average (range, 1 to 2). Significant post-treatment volume reductions were noted; however, the EA group showed a higher volume reduction than the RFA group at 1 (78.7%-16.1% vs. 49.1%-15.8%), 6 (86.3%-21.7% vs. 73.0%-14.5%), and 12 (90.9%-14.9% vs. 80.3%-12.4%) months. The score for each scale of the QoL questionnaire improved significantly during follow-up (all P<0.001). Overall QoL improved significantly, from 1.7±0.9 at diagnosis to 0.6±0.7 at the 12-month follow-up (P<0.001). There were no major complications.
conclusionBoth RFA and EA are safe and effective in reducing nodule volume and improving thyroid-specific QoL in patients with BSTNs.
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