SynthesisJournal of clinical periodontology2022
Pocket closure and residual pockets after non-surgical periodontal therapy: A systematic review and meta-analysis.
Synthesis in Journal of clinical periodontology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05757921 (Non-surgical Treatment of Periodontitis With or Without the Adjunctive Treatment of Perisolv®), which is not on this map. Cited by 38 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Non-surgical Treatment of Periodontitis With or Without the Adjunctive Treatment of Perisolv®
Who cites it
38 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Efficacy of different protocols of non-surgical periodontal therapy in patients with type 2 diabetes: A systematic review and meta-analysis.Journal of periodontal research · 2025Pooled it
- The long-term efficacy of tetracycline class antimicrobials as local adjuncts in the treatment of chronic periodontitis: a systematic review and meta-analysis.Frontiers in dental medicine · 2025Pooled it
- Laser treatments as an adjunct to non-surgical periodontal therapy in subjects with periodontitis and type 2 diabetes mellitus: a systematic review and meta-analysis.Clinical oral investigations · 2023Pooled it
- Pocket closure and residual pockets after non-surgical periodontal therapy: A systematic review and meta-analysis.Journal of clinical periodontology · 2022Pooled it
- App-supported powered toothbrushing during non-surgical periodontal therapy in stage III-IV periodontitis: a secondary analysis of a randomized controlled trial.BMC oral health · 2026Trial
- Does minimally invasive non-surgical therapy improve outcomes in splinted mandibular incisors? Results from a randomized trial.BMC oral health · 2026Trial
- Timing of Re-Evaluation After Periodontal Therapy: A Randomized Clinical Trial.Journal of periodontal research · 2026Trial
- Clinical efficacy and patient-reported outcomes of coconut oil as adjunctive periodontitis treatment: triple-blinded pilot randomized trial.BMC oral health · 2026Trial
- Non-surgical periodontal therapy with and without hyaluronic acid gel in type 2 diabetic stage-II periodontitis patients: a randomized clinical trial.BMC oral health · 2025Trial
- Airflowing as an adjunctive treatment for periodontitis: A randomized controlled trial.Journal of periodontology · 2024Trial
- Supra- and sub-gingival instrumentation of periodontitis with the adjunctive treatment of a chloramine - a one-year randomized clinical trial study.Acta odontologica Scandinavica · 2024Trial
- Influence of Staging and Grading and Multiple Factors on the Success of Non-Surgical Periodontal Therapy Performed by Dental Hygienists: A Retrospective Analysis.International journal of dental hygiene · 2026Article
- Progression of Furcation Involvement: A Multi-Center Cohort Study of Incidence, Timing, and Risk Factors.Journal of periodontal research · 2026Article
- [Short-term efficacy and influencing factors of systemic antibiotics as an adjunct to mechanical periodontal therapy for stages Ⅲ/Ⅳ periodontitis].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026Article
- Local drug delivery systems for the periodontal microenvironment: from barrier penetration to multilevel synergy.Frontiers in pharmacology · 2026Review
- Interplay between dietary antioxidants and oxidative/nitrosative stress in stage III periodontitis: a preliminary quasi-experimental study in a Mexican population.Frontiers in oral health · 2026Article
- Molecular cytokine-dependent mechanisms of periodontitis pathogenesis and the potential for pharmacological IL-1 modulation in disease treatment.Frontiers in dental medicine · 2026Review
- Sodium Hypochlorite/Amino Acid Gel in the Non-Surgical Treatment of Periodontitis-Clinical and Molecular Results of Randomized Clinical Trial.Journal of functional biomaterials · 2025Article
- Multi-Omics Signatures of Periodontitis and Periodontal Therapy on the Oral and Gut Microbiome.Journal of periodontal research · 2025Article
- Impact of lifestyle behaviors on clinical outcomes of steps 1 and 2 of periodontal therapy in stage iii-iv periodontitis: a cohort study.Clinical oral investigations · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo analyse the efficacy of non-surgical therapy (NST) in terms of pocket closure (PC) and changes in percentage and number of pockets. MATERIALS AND
methodsThree databases (PubMed, EMBASE, and Scopus) were searched up to January 2020. Prospective studies with a minimum follow-up of 12 months and presenting data in terms of PC or number or percentage of pocket depths (PDs) before and after NST on systemically healthy patients were included. Random-effect meta-analyses were performed.
resultsAfter screening 4610 titles and abstracts, 27 studies were included. Of these, 63.9% of PC was reported by one study. The percentage of PDs ≤3 mm changed from 39.06% to 64.11% with a weighted mean difference (WMD) of 26.14% (p < .001). This accounted for a relative increase of healthy sites of 64.13%. The mean percentage of PD ≥5 mm was 28.23% and 11.71% before and after treatment, respectively, with a WMD of 15.50% (p < .001). The WMD in the number of PDs ≥5 mm before and after treatment was 24.42 (p = .036). The mean number of residual PPD ≥5 after NST was 14.13.
conclusionsNST is able to eradicate the majority of the pockets. However, residual pockets after NST may remain and should be considered cautiously for further treatment planning.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.