ArticleJournal of affective disorders2021
Stressful life events and openness to experience: Relevance to depression.
Article in Journal of affective disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 48 citations in OpenAlex.
- Depression meets obesity: Co-occurrence patterns, temporal trends and socioeconomic correlates across 199 countries and territories.General psychiatry · 2026Article
- Are Adolescents with Higher Openness More Creative Under Stress? The Mediating Role of Stress Perception and Cognitive Flexibility.Journal of Intelligence · 2026Article
- The effect of physical activity and life events on mental health of college students: the mediating role of psychological vulnerability.BMC psychology · 2025Article
- Moral emotions and auditory verbal hallucinations in schizophrenia.Schizophrenia (Heidelberg, Germany) · 2025Review
- Perceived stress and life satisfaction among university students: the mediating and moderating roles of coping strategies and personality traits.Frontiers in psychology · 2025Article
- Prenatal Attachment, Personality, and Depression in High-Risk Pregnancies During Pandemic Emergencies.Healthcare (Basel, Switzerland) · 2024Article
- Testing of significant changes in big-five personality factors over time in the presence and absence of memory impairment and life-related stress.Scientific reports · 2024Article
- Multiple sclerosis and personality traits: associations with depression and anxiety.European journal of medical research · 2024Article
- Stress events and stress symptoms in Chinese secondary school students: gender and academic year characteristics of the relationship.Frontiers in public health · 2024Article
- Chronic pain as an emergent property of a complex system and the potential roles of psychedelic therapies.Frontiers in pain research (Lausanne, Switzerland) · 2024Article
- The mediating effects of dysfunctional attitudes and moderating effect of sex between stressful life events and depressive symptoms among Chinese college students.Scientific reports · 2023Article
- The Bridge between Cybervictimization and Suicidal Ideation among Adolescents: A Vicious Cycle of Hopelessness.Journal of youth and adolescence · 2023Article
- Depression, stress and regional cerebral blood flow.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- The Relationship Between Personality Traits and Clinical Decision-Making, Anxiety and Stress Among Intern Nursing Students During COVID-19: A Cross-Sectional Study.Psychology research and behavior management · 2023Article
- The Big Five Personality Traits as Predictors of Negative Emotional States in University Students in Taiwan.International journal of environmental research and public health · 2022Article
- Behavioral Patterns of Depression Patients and Control Population.International journal of environmental research and public health · 2022Article
- Cross-Sectional Associations between Living and Built Environments and Depression Symptoms among Chinese Older Adults.International journal of environmental research and public health · 2022Article
- Exploring the path of persisting dysfunctional expectations-Development of the immunization scale IMS.Frontiers in psychology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundStressful life events are known as risk factors for depression, though there is considerable heterogeneity in how people respond to stress. Previous studies have found an association between experience of stressful life events and the personality trait of openness to experience, which itself has been associated with intelligence, creativity, risk-taking, and other clinically relevant behaviors. In this study we explore the association between stressful life events and openness to experience as a potential developmental pathway to depression in the Amish and Mennonites, rural populations with high degree of social and environmental homogeneity.
methodsParticipants in the Amish Connectome Project (n=531) were assessed with the NEO personality inventory, Beck Depression Inventory, Maryland Trait and State Depression scales, a Life Stressors Inventory, and cognitive tests.
resultsWe found that stressful life events were significantly associated with openness to experience; that participants with a history of depression exhibited higher levels of openness; and that openness to experience was related to overall intelligence but not processing speed or working memory. We found evidence that openness to experience partially mediates the relationship between stressful life events and depression. LIMITATIONS: This was a cross-sectional study, limiting interpretation of causal pathways. High levels of inter-relatedness among participants may have led to exaggerated effects compared to the general population.
conclusionsTogether these findings indicate a complex developmental influence of major stressful life events, which paradoxically by enhancing openness may be associated with both greater intellectual engagement as well as psychopathology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.