ArticleNeuroImage2021
Spontaneous cortical MEG activity undergoes unique age- and sex-related changes during the transition to adolescence.
Article in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 40 citations in OpenAlex.
- Implicitly tuned: The neural effects of social feedback on adolescent learning.Developmental cognitive neuroscience · 2026Article
- From Developmental Timing to Clinical Visibility: An Integrative Narrative Review of Sex-Related Neurocognitive Development.Children (Basel, Switzerland) · 2026Review
- Normative modeling of MEG brain oscillations across the human lifespan.Communications biology · 2026Article
- Females have shorter scalp-to-cortex distances and receive stronger TMS electrical fields: Implications for clinical treatment.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Electrophysiological sexual dimorphism as an early risk marker of alcohol use in adolescence: A longitudinal neuroimaging study.Addiction (Abingdon, England) · 2026Article
- Confirmation of a Useful Dark-Room Resting-State Procedure: Periodic and Aperiodic MEG Activity in Children.Psychophysiology · 2026Article
- Disruption of brain rhythms in a pharmacological model of schizophrenia in male and female mice.Biology of sex differences · 2025Article
- Spatiotemporal dynamics of multispectral oscillatory activity underlying the processing of negative and positive emotional images.NeuroImage · 2025Article
- Multi-centre normative brain mapping of intracranial EEG lifespan patterns in the human brain.Brain structure & function · 2025Article
- Oscillatory brain dynamics underlying affective face processing.Social cognitive and affective neuroscience · 2025Article
- Interactive effects of social media use and puberty on resting-state cortical activity and mental health symptoms.Developmental cognitive neuroscience · 2025Article
- Developmental shifts in testosterone levels are associated with alterations in the neural oscillatory dynamics serving selective attention.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Chronic Cannabis users exhibit altered oscillatory dynamics and functional connectivity serving visuospatial processing.Journal of psychopharmacology (Oxford, England) · 2024Article
- Article
- Sex-specific Differences in Resting Oscillatory Dynamics in Children with Prenatal Alcohol Exposure.Neuroscience · 2024Article
- The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study.bioRxiv : the preprint server for biology · 2024Article
- From bench to bedside: Overview of magnetoencephalography in basic principle, signal processing, source localization and clinical applications.NeuroImage. Clinical · 2024Review
- Sexual dimorphism in cortical theta rhythms relates to elevated internalizing symptoms during adolescence.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Developmental changes in endogenous testosterone have sexually-dimorphic effects on spontaneous cortical dynamics.Human brain mapping · 2023Article
- ImageNomer: Description of a functional connectivity and omics analysis tool and case study identifying a race confound.Neuroimage. Reports · 2023Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundWhile numerous studies have examined the developmental trajectory of task-based neural oscillations during childhood and adolescence, far less is known about the evolution of spontaneous cortical activity during this time period. Likewise, many studies have shown robust sex differences in task-based oscillations during this developmental period, but whether such sex differences extend to spontaneous activity is not understood.
methodsHerein, we examined spontaneous cortical activity in 111 typically-developing youth (ages 9-15 years; 55 male). Participants completed a resting state magnetoencephalographic (MEG) recording and a structural MRI. MEG data were source imaged and the power within five canonical frequency bands (delta, theta, alpha, beta, gamma) was computed. The resulting power spectral density maps were analyzed via vertex-wise ANCOVAs to identify spatially-specific effects of age, sex, and their interaction.
resultsWe found robust increases in power with age in all frequencies except delta, which decreased over time, with findings largely confined to frontal cortices. Sex effects were distributed across frontal and temporal regions; females tended to have greater delta and beta power, whereas males had greater alpha. Importantly, there was a significant age-by-sex interaction in theta power, such that males exhibited decreasing power with age while females showed increasing power with age in the bilateral superior temporal cortices. DISCUSSION: These data suggest that the strength of spontaneous activity undergoes robust change during the transition from childhood to adolescence (i.e., puberty onset), with intriguing sex differences in some cortical areas. Future developmental studies should probe task-related oscillations and spontaneous activity in parallel.
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