Evidence map›Paper›PMID 34517047›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2021

Anal human papillomavirus prevalence and risk factors among men who have sex with men in Vietnam.

Le Anh Tuan, Kiesha Prem, Quang Duy Pham, Zheng Quan Toh, Hau Phuc Tran, Phuc Duy Nguyen, Chu Thi Ngoc Mai, Le Thi Khanh Ly, Van Cao, Tam-Duong Le-Ha and 9 more

Registry-linked trialAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06681636 (A Non-inferiority Study Comparing the Immunogenicity of a Standard or an Extended Three-dose Nonavalent Human Papillomavirus Vaccine Schedule Between High-risk Women Aged 18-26 Years and Age-matched Women in the General Population), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06681636 phase2not yet recruitingnot on this mapstarted 2024, after this paper: background citation

A Non-inferiority Study Comparing the Immunogenicity of a Standard or an Extended Three-dose Nonavalent Human Papillomavirus Vaccine Schedule Between High-risk Women Aged 18-26 Years and Age-matched Women in the General Population

TypeinterventionalSponsorNational Institute of Hygiene and Epidemiology, VietnamRan2024 to 2027Enrolled300ConditionsHPV Infection, Cervical Cancer, Anogenital Cancer, Anogenital WartsArmsHuman papillomavirus 9-valent vaccine, Recombinant
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Le Anh TuanNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam. Electronic address: lat@nihe.org.
Kiesha PremLondon School of Hygiene and Tropical Medicine, London, UK. Electronic address: kiesha.prem@lshtm.ac.uk.
Quang Duy PhamPasteur Institute in Ho Chi Minh City, Ho Chi Minh City, Vietnam. Electronic address: duyquang.pham@gmail.com.
Zheng Quan TohInfection and Immunity, Murdoch Children's Research Institute, VIC, Australia; Department of Paediatrics, The University of Melbourne, VIC, Australia. Electronic address: zheng.quantoh@mcri.edu.au.
Hau Phuc TranPasteur Institute in Ho Chi Minh City, Ho Chi Minh City, Vietnam. Electronic address: hautran68@gmail.com.
Phuc Duy NguyenPasteur Institute in Ho Chi Minh City, Ho Chi Minh City, Vietnam. Electronic address: phucnguyenduy@gmail.com.
Chu Thi Ngoc MaiNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam. Electronic address: chumai93@gmail.com.
Le Thi Khanh LyNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam. Electronic address: lethikhanhlyb_t59@hus.edu.vn.
Van CaoPasteur Institute in Ho Chi Minh City, Ho Chi Minh City, Vietnam. Electronic address: vancao.pasteur@gmail.com.
Tam-Duong Le-HaPasteur Institute in Ho Chi Minh City, Ho Chi Minh City, Vietnam. Electronic address: lehatamduong@gmail.com.
Nguyen Anh TuanNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam. Electronic address: nat@nihe.org.vn.
Mark JitLondon School of Hygiene and Tropical Medicine, London, UK; School of Public Health, University of Hong Kong, Hong Kong, SAR, China; Public Health England, Modelling and Economics Unit, London, UK. Electronic address: mark.jit@lshtm.ac.uk.
Kathryn BrightInfection and Immunity, Murdoch Children's Research Institute, VIC, Australia. Electronic address: kathrynbright59@gmail.com.
Marc BrissonCentre de recherche du CHU de Québec, Université Laval, Québec, QC, Canada; Department of Social and Preventive Medicine, Université Laval, Québec, Canada. Electronic address: marc.brisson@crchudequebec.ulaval.ca.
Thuong Vu NguyenPasteur Institute in Ho Chi Minh City, Ho Chi Minh City, Vietnam. Electronic address: nguyenthuong@yahoo.com.
Suzanne GarlandInfection and Immunity, Murdoch Children's Research Institute, VIC, Australia; Centre for Women's Infectious Diseases, The Royal Women's Hospital, Melbourne, Department of Obstetrics and Gynaecology, University of Melbourne, Australia. Electronic address: suzanne.garland@thewomens.org.au.
Dang Duc AnhNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam. Electronic address: dda@nihe.org.vn.
Nguyen Van TrangNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam. Electronic address: nvt@nihe.org.vn.
Kim MulhollandLondon School of Hygiene and Tropical Medicine, London, UK; Infection and Immunity, Murdoch Children's Research Institute, VIC, Australia; Department of Paediatrics, The University of Melbourne, VIC, Australia. Electronic address: Kim.Mulholland@lshtm.ac.uk.

Funding

Medical Research Council MR/N028473/1
6 · The paper itself

Abstract

objectivesMen who have sex with men (MSM) are at risk of human papillomavirus (HPV)-related cancers, while published data are scarce. This study determined HPV prevalence and risk factors in MSM in Vietnam to inform HPV prevention strategies in this key population.

methodsA cross-sectional study of 799 MSM aged 16-50 years was conducted in Vietnam in 2017-2018. Information was collected on risk behaviours, and knowledge of HPV and anal cancer; rectal swabs were taken to detect anal HPV infection. An in-house polymerase chain reaction and Genoflow HPV array test kit were used for HPV detection and genotyping.

resultsThe median age of the study participants was 25 years (range 18-52). Overall prevalence of any HPV and HPV16/18 infection was 32.3% and 11.0%, respectively. A higher prevalence of high-risk HPV infection to all 14 types tested was found in Ho Chi Minh City (30.9%) than in Hanoi (18.4%). High-risk HPV infection was associated with inconsistent condom use and history of engaging in sex under the influence of drugs (adjusted odds ratio (aOR), 2.27; 95% CI, 1.48-10.67), as well as having multiple sexual partners (aOR, 1.01; 95% CI, 1.00-1.02).

conclusionsHigh-risk anal HPV infections in Vietnamese MSM were significantly associated with risky sexual behaviours. A targeted HPV vaccination strategy would have substantial benefit for MSM in Vietnam.

Indexed as

AlphapapillomavirusHIV InfectionsPapillomavirus InfectionsSexual and Gender MinoritiesAdolescentAdultCross-Sectional StudiesHomosexuality, MaleHuman papillomavirus 16Human papillomavirus 18HumansMaleMiddle AgedPapillomaviridaePrevalenceRisk FactorsHPVMen who have sex with menMSMRisk factorsVietnam

Identifiers

PMID34517047
PMCPMC8627386

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.