Evidence map›Paper›PMID 34516956›Full record

ArticlePhysiology & behavior2021

The effects of acute exercise on appetite and energy intake in men and women.

Selene Y Tobin, Marc-Andre Cornier, Mollie H White, Allison K Hild, Sara E Simonsen, Edward L Melanson, Tanya M Halliday

Erratum issuedAbstract read
In one paragraph

Article in Physiology & behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Systematic Review: Does Exercise Training Influence Ghrelin Levels?International journal of molecular sciences · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Review
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  9. Article
  10. Role of Leu72Met ofNutrients · 2022
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Selene Y TobinDepartment of Health and Kinesiology, College of Health, University of Utah, 250 S 1850 E., Salt Lake City, UT 84112, United States.
Marc-Andre CornierDivision of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, United States; Anschutz Health & Wellness Center at the University of Colorado, Anschutz Medical Campus, Aurora, Colorado, United States; Rocky Mountain Regional Veterans Administration, Aurora, Colorado, United States.
Mollie H WhiteAnschutz Health & Wellness Center at the University of Colorado, Anschutz Medical Campus, Aurora, Colorado, United States.
Allison K HildAnschutz Health & Wellness Center at the University of Colorado, Anschutz Medical Campus, Aurora, Colorado, United States.
Sara E SimonsenCollege of Nursing, University of Utah, Salt Lake City, United States.
Edward L MelansonDivision of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, United States; Rocky Mountain Regional Veterans Administration, Aurora, Colorado, United States; Division of Geriatric Medicine, Department of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, United States.
Tanya M HallidayDepartment of Health and Kinesiology, College of Health, University of Utah, 250 S 1850 E., Salt Lake City, UT 84112, United States; Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, United States. Electronic address: tanya.halliday@utah.edu.

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
NIDDK National Research Service Award (NRSA) T32 Diversity Administrative SupplementT32DK007658 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Kristen Elizabeth Boyle, Ihuoma U Eneli · 1991 to 2026
$6.0M
TRAINING PROGRAM IN DIABETES, ENDOCRINOLOGY &METABOLISMT32DK007446 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BESSESEN, DANIEL HOLLAND · 1986 to 2017
$5.6M
Vascular Health and Risk Factors in Children with Down SyndromeKL2TR002539 · NCATS · UNIVERSITY OF UTAH · PI MURTAUGH, MAUREEN A, NYGAARD, INGRID E · 2018 to 2022
$4.3M
NCATS NIH HHS KL2 TR002539NCATS NIH HHS UL1 TR002535NCATS NIH HHS UL1 TR002538NIDDK NIH HHS P30 DK048520NIDDK NIH HHS T32 DK007446NIDDK NIH HHS T32 DK007658
6 · The paper itself

Abstract

purposeTo compare energy intake (EI) and appetite regulation responses between men and women following acute bouts of aerobic (AEx), resistance exercise (REx), and a sedentary control (CON).

methodsMen and women (n = 24; 50% male) with overweight/obesity, matched on age (32.3 ± 2 vs. 36.8 ± 2 yrs, p = 0.14) and BMI (28.1 ± 1.2 vs 29.0 ± 1.5 kg/m2, p = 0.64) completed 3 conditions: 1) AEx (65-70% of age-predicted maximum heart rate for 45 min); 2) REx (1-set to failure on 12 exercises); and 3) CON. Each condition was initiated in the post-prandial state (35 min following consumption of a standardized breakfast). Appetite (visual analog scale for hunger, satiety, and prospective food consumption [PFC]) and hormones (ghrelin, PYY, and GLP-1) were measured in the fasted state and every 30 min post-prandially for 3 h. Post-exercise ad libitum EI at the lunch meal was also measured.

resultsMen reported higher levels of hunger compared to women across all study conditions (AEx: Men: 7815.00 ± 368.3; Women: 5428.50 ± 440.0 mm x 180 min; p = 0.025; REx: Men: 7110.00 ± 548.4; Women: 6086.25 ± 482.9 mm x 180 min; p = 0.427; CON: Men: 8315.00 ± 429.8; Women: 5311.25 ± 543.1 mm x 180 min; p = 0.021) and consumed a greater absolute caloric load than women at the ad libitum lunch meal (AEx: Men: 1021.6 ± 105.4; Women: 851.7 ± 70.5 kcals; p = 0.20; REx: Men: 1114.7 ± 104.0; Women: 867.7 ± 76.4 kcals; p = 0.07; CON: Men: 1087.0 ± 98.8; Women: 800.5 ± 102.3 kcals; p = 0.06). However, when adjusted for relative energy needs, there was no difference in relative ad libitum EI observed between men and women. No differences in Area Under the Curve for Satiety, PFC, ghrelin, PYY, and GLP-1 were noted between men and women following acute exercise (all p > 0.05).

conclusionsThese data suggest that women report lower ratings of appetite following an acute bout of exercise or sedentary time when compared to men, yet have similar relative EI. Future work is needed to examine whether sex-based differences in appetite regulation and EI are present with chronic exercise of differing modalities.

Indexed as

AppetiteEnergy IntakeCross-Over StudiesExerciseFemaleGhrelinHumansMaleProspective StudiesSatiationGhrelinAppetite regulationEating behaviorsResistance exerciseSex-based differences

Identifiers

PMID34516956
PMCPMC8627323

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.