ArticleScience advances2021
3D printed personalized magnetic micromachines from patient blood-derived biomaterials.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Genetically engineered human cell-based microrobots for selective cancer cell death.Science advances · 2026Article
- Deployable 3D-Printed Vascular Stent with Surface-Catalysed Endogenous Nitric Oxide Generation.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Enzymatic microbubble robots.Nature nanotechnology · 2026Article
- Functional biomaterials for the treatment of periprosthetic joint infection: A systematic review of preclinical animal studies.Journal of orthopaedic translation · 2026Review
- Magnetic and pneumatic actuation of polymeric microneedles for plasmonic hot-spot engineering and molecular sensing.Nature communications · 2025Article
- Modular magnetic microrobot system for robust endoluminal navigation and high-radial force stent delivery in complex ductal anatomy.Science advances · 2025Article
- Metal Oxide-Functionalized Photopolymers: A Perspective in 3D Printing.ACS polymers Au · 2025Review
- Fabrication of Organic/Inorganic Nanocomposites: From Traditional Synthesis to Additive Manufacturing.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Machining swarf formation-inspired fabrication of ferrofluidic helical miniature robots with multimodal locomotion capability.Science advances · 2025Article
- Femtosecond laser-assisted printing of hard magnetic microrobots for swimming upstream in subcentimeter-per-second blood flow.Science advances · 2025Article
- Quadrupole Magnetic Tweezers for Precise Cell Transportation.IEEE transactions on bio-medical engineering · 2025Article
- Trends in Photopolymerization 3D Printing for Advanced Drug Delivery Applications.Biomacromolecules · 2025Review
- Article
- Developing fibrin-based biomaterials/scaffolds in tissue engineering.Bioactive materials · 2024Review
- Designing magnetic microcapsules for cultivation and differentiation of stem cell spheroids.Microsystems & nanoengineering · 2024Article
- Capillary trapping of various nanomaterials on additively manufactured scaffolds for 3D micro-/nanofabrication.Nature communications · 2024Article
- Zwitterion-Lubricated Hydrogel Microspheres Encapsulated with Metformin Ameliorate Age-Associated Osteoarthritis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Eco-friendly bio-nanocomposites: pioneering sustainable biomedical advancements in engineering.Discover nano · 2024Review
- State of the Art in Actuation of Micro/Nanorobots for Biomedical Applications.Small science · 2024Article
- tPA-anchored nanorobots for in vivo arterial recanalization at submillimeter-scale segments.Science advances · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While recent wireless micromachines have shown increasing potential for medical use, their potential safety risks concerning biocompatibility need to be mitigated. They are typically constructed from materials that are not intrinsically compatible with physiological environments. Here, we propose a personalized approach by using patient blood–derivable biomaterials as the main construction fabric of wireless medical micromachines to alleviate safety risks from biocompatibility. We demonstrate 3D printed multiresponsive microswimmers and microrollers made from magnetic nanocomposites of blood plasma, serum albumin protein, and platelet lysate. These micromachines respond to time-variant magnetic fields for torque-driven steerable motion and exhibit multiple cycles of pH-responsive two-way shape memory behavior for controlled cargo delivery and release applications. Their proteinaceous fabrics enable enzymatic degradability with proteinases, thereby lowering risks of long-term toxicity. The personalized micromachine fabrication strategy we conceptualize here can affect various future medical robots and devices made of autologous biomaterials to improve biocompatibility and smart functionality.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.