Evidence map›Paper›PMID 34516320›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2022

Postoperative cognitive dysfunction after endovascular treatments for unruptured intracranial aneurysms: A pilot study.

Daizo Ishii, Mario Zanaty, Jorge A Roa, Luyuan Li, Yongjun Lu, Lauren Allan, Edgar A Samaniego, James C Torner, Daniel Tranel, David M Hasan

Open access · greenAbstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Daizo IshiiDepartment of Neurosurgery, 21782University of Iowa Hospitals and Clinics, USA.ORCID https://orcid.org/0000-0002-7139-695X
Mario ZanatyDepartment of Neurosurgery, 21782University of Iowa Hospitals and Clinics, USA.
Jorge A RoaDepartment of Neurology, 21782University of Iowa Hospitals and Clinics, USA.
Luyuan LiDepartment of Neurosurgery, 21782University of Iowa Hospitals and Clinics, USA.
Yongjun LuDepartment of Neurosurgery, 21782University of Iowa Hospitals and Clinics, USA.
Lauren AllanDepartment of Surgery, 21782University of Iowa Hospitals and Clinics, USA.
Edgar A SamaniegoDepartment of Neurology, 21782University of Iowa Hospitals and Clinics, USA.
James C TornerDepartment of Epidemiology, University of Iowa, USA.
Daniel TranelDepartment of Neurology, 21782University of Iowa Hospitals and Clinics, USA.
David M HasanDepartment of Neurosurgery, 21782University of Iowa Hospitals and Clinics, USA.ORCID https://orcid.org/0000-0002-8335-5442
University of Iowa Hospitals and Clinics · USUniversity of Iowa · US

Funding

PROGRAM IN HEMOSTASIS AND THROMBOSIS FOR ACADEMICT32HL007344 · NHLBI · UNIVERSITY OF IOWA · PI Anil Kumar Chauhan, Steven R Lentz · 1985 to 2026
$6.5M
NHLBI NIH HHS T32 HL007344
6 · The paper itself

Abstract

objectivePost operative cognitive dysfunction (POCD) has been widely observed after major surgery, particularly in elderly patients with general anesthesia (GA). However, a specific unanswered question is whether different approaches to anesthetic managements are associated with different cognitive outcomes after endovascular treatments for unruptured intracranial aneurysms (UIAs). The purpose of this study is to assess the correlation of POCD with GA versus monitored anesthesia care (MAC).

methodsWe performed a pragmatic, prospective study to assess the association between different anesthetic approaches and POCD. We compared the pre- and post-procedural Montreal Cognitive Assessment (MoCA) scores in patients with normal cognition who underwent treatments of UIAs with various endovascular methods, using either GA or MAC.

resultsA total of 23 patients with UIAs were enrolled in the study. Seven (30.4%) and sixteen (69.6%) UIAs were treated without perioperative complications under GA or MAC, respectively. There was a significant decline in the post-procedural MoCA score under GA (mean difference  =  1.14; 95% confidence interval  =  [0.42-1.87],

conclusionsTreating UIAs using MAC was associated with a decrease in POCD as compared to GA in patients undergoing endovascular treatments for UIAs with normal cognition. Larger randomized studies are needed to confirm these findings.

Indexed as

Intracranial AneurysmPostoperative Cognitive ComplicationsAgedHumansPilot ProjectsPostoperative ComplicationsProspective StudiesTreatment OutcomeEndovascular treatmentgeneral anesthesiaintracranial aneurysmmonitored anesthesia carepostoperative cognitive dysfunction

Identifiers

PMID34516320
PMCPMC9326860
OpenAlexW3199771907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.