Evidence map›Paper›PMID 34516296›Full record

ArticleEnvironmental health perspectives2021

Ambient Air Pollution and Long-Term Trajectories of Episodic Memory Decline among Older Women in the WHIMS-ECHO Cohort.

Xinhui Wang, Diana Younan, Andrew J Petkus, Daniel P Beavers, Mark A Espeland, Helena C Chui, Susan M Resnick, Margaret Gatz, Joel D Kaufman, Gregory A Wellenius and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Xinhui WangDepartment of Neurology, University of Southern California, Los Angeles, California, USA.
Diana YounanDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, California, USA.
Andrew J PetkusDepartment of Neurology, University of Southern California, Los Angeles, California, USA.
Daniel P BeaversDepartment of Biostatistics and Data Sciences, Wake Forest School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.
Mark A EspelandDepartment of Biostatistics and Data Sciences, Wake Forest School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.
Helena C ChuiDepartment of Neurology, University of Southern California, Los Angeles, California, USA.
Susan M ResnickLaboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland, USA.
Margaret GatzCenter for Economic and Social Research, University of Southern California, Los Angeles, California, USA.
Joel D KaufmanDepartments of Environmental & Occupational Health Sciences, Medicine (General Internal Medicine), and Epidemiology, University of Washington, Seattle, Washington, USA.
Gregory A WelleniusDepartment of Environmental Health, Boston University, Boston, Massachusetts, USA.
Eric A WhitselDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
JoAnn E MansonBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Jiu-Chiuan ChenDepartment of Neurology, University of Southern California, Los Angeles, California, USA.
University of Southern California · USWake Forest University · USBoston University · USBrigham and Women's Hospital · USNational Institutes of Health · USUniversity of North Carolina at Chapel Hill · USUniversity of Washington · US

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Joseph Leo Wiemels · 1996 to 2026
$46.4M
XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI ALI SHOJAIE · 1995 to 2026
$42.5M
VASCULAR RISK AND COGNITIVE STATUS IN A LATINO POPULATIONP50AG005142 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ARANDA, MARIA P. · 1985 to 2019
$41.0M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3M
Research Education ComponentP30AG066514 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI NIKOLAOS K ROBAKIS · 2020 to 2026
$31.0M
USCADRC Diversity Supplement PachicanoP30AG066530 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HELENA Chang CHUI, ARTHUR W TOGA · 2020 to 2026
$27.8M
Wake Forest Alzheimer's Disease Core CenterP30AG049638 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI RAPP, STEPHEN R · 2016 to 2020
$12.2M
Urban Air Pollution and Pathological Brain Aging: A Nationwide Twin Study in MenP01AG055367 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MACK, WILLIAM J · 2018 to 2022
$11.5M
Alzheimer's Disease & Related Dementias: Geography, Environments, and MechanismsRF1AG054068 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, JIU-CHIUAN · 2016 to 2016
$4.1M
Environmental Determinants of Pathological Brain Aging in WHI Memory StudiesR01ES025888 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, JIU-CHIUAN, KAUFMAN, JOEL DANIEL · 2016 to 2020
$3.2M
Ambient Air Pollution and Incident StrokeR01ES020871 · NIEHS · BROWN UNIVERSITY · PI WELLENIUS, GREGORY A · 2012 to 2016
$2.7M
Air pollution, the social environment, and Alzheimer's disease: Risk and resilience in the Ginkgo Evaluation Memory StudyRF1AG057033 · NIA · UNIVERSITY OF WASHINGTON · PI FITZPATRICK, ANNETTE L., KAUFMAN, JOEL DANIEL · 2017 to 2017
$2.3M
NHLBI NIH HHS HHSN268201600001CNHLBI NIH HHS HHSN268201600002CNHLBI NIH HHS HHSN268201600003CNHLBI NIH HHS HHSN268201600004CNHLBI NIH HHS HHSN268201600018CNIA NIH HHS P01 AG055367NIA NIH HHS P30 AG049638NIA NIH HHS P30 AG066514NIA NIH HHS P30 AG066530NIA NIH HHS P50 AG005142NIA NIH HHS RF1 AG054068NIA NIH HHS RF1 AG057033NIEHS NIH HHS P30 ES007033NIEHS NIH HHS P30 ES007048NIEHS NIH HHS P30 ES010126NIEHS NIH HHS R01 ES020871NIEHS NIH HHS R01 ES025888
6 · The paper itself

Abstract

backgroundEpisodic memory decline varies by age and underlying neuropathology. Whether ambient air pollution contributes to the heterogeneity of episodic memory decline in older populations remains unclear.

objectivesWe estimated associations between air pollution exposures and episodic memory decline according to pollutant, exposure time window, age, and latent class subgroups defined by episodic memory trajectories.

methodsParticipants were from the Women's Health Initiative Memory Study-Epidemiology of Cognitive Health Outcomes. Older women (

resultsTwo latent classes were identified for women DISCUSSION: In a community-dwelling U.S. population of older women, associations between late-life exposure to ambient air pollution and episodic memory decline varied by age-related cognitive trajectories, exposure time windows, and pollutants. https://doi.org/10.1289/EHP7668.

Indexed as

Air PollutantsAir PollutionMemory, EpisodicAgedEnvironmental ExposureFemaleHumansParticulate MatterAir PollutantsParticulate Matter

Identifiers

PMID34516296
PMCPMC8437247
OpenAlexW3199313493

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.