Evidence map›Paper›PMID 34516284›Full record

ArticleJournal of bacteriology2021

A Shift to Human Body Temperature (37°C) Rapidly Reprograms Multiple Adaptive Responses in Escherichia coli That Would Facilitate Niche Survival and Colonization.

Anastasia Gant Kanegusuku, Isidora N Stankovic, Pamela A Cote-Hammarlof, Priscilla H Yong, Christine A White-Ziegler

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anastasia Gant KanegusukuDepartment of Biological Sciences, Smith Collegegrid.263724.6, Northampton, Massachusetts, USA.
Isidora N StankovicProgram in Biochemistry, Smith Collegegrid.263724.6, Northampton, Massachusetts, USA.
Pamela A Cote-HammarlofDepartment of Biological Sciences, Smith Collegegrid.263724.6, Northampton, Massachusetts, USA.
Priscilla H YongProgram in Biochemistry, Smith Collegegrid.263724.6, Northampton, Massachusetts, USA.
Christine A White-ZieglerDepartment of Biological Sciences, Smith Collegegrid.263724.6, Northampton, Massachusetts, USA.
Smith College · US

Funding

Short-term responses to temperature changes in Escherichia coliR15GM093908 · NIGMS · SMITH COLLEGE · PI WHITE-ZIEGLER, CHRISTINE A · 2010 to 2010
$392k
Howard Hughes Medical InstituteNIGMS NIH HHS 1R15GM93908-1NIGMS NIH HHS R15 GM093908
6 · The paper itself

Abstract

One of the first environmental cues sensed by a microbe as it enters a human host is an upshift in temperature to 37°C. In this dynamic time point analysis, we demonstrate that this environmental transition rapidly signals a multitude of gene expression changes in Escherichia coli. Bacteria grown at 23°C under aerobic conditions were shifted to 37°C, and mRNA expression was measured at time points after the shift to 37°C (

Indexed as

Body TemperatureBacterial Outer Membrane ProteinsCarrier StateEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialGenome, BacterialHumansProtein Array AnalysisReverse Transcriptase Polymerase Chain ReactionTemperatureBacterial Outer Membrane ProteinsEscherichia coli Proteinsanaerobic respirationbiofilmbiofilmsRpoSstress responsetemperaturetranscriptional regulationtranscriptomevirulence

Identifiers

PMID34516284
PMCPMC8544407
OpenAlexW3200993369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.