Evidence map›Paper›PMID 34516282›Full record

ReviewJournal of bacteriology2022

Bacterial Small Membrane Proteins: the Swiss Army Knife of Regulators at the Lipid Bilayer.

Srujana S Yadavalli, Jing Yuan

Open access · greenAbstract readReview
In one paragraph

Review in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Analysis of stress-induced small proteins inbioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Molecules (Basel, Switzerland) · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Large Roles of Small Proteins.Annual review of microbiology · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Srujana S YadavalliWaksman Institute of Microbiology, Rutgers University, Piscataway, New Jersey, USA.ORCID 0000-0002-4335-1973
Jing YuanMax Planck Institute for Terrestrial Microbiology, Marburg, Germany.ORCID 0000-0003-1219-3316
Loewe Center for Synthetic Microbiology · DERutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small membrane proteins represent a subset of recently discovered small proteins (≤100 amino acids), which are a ubiquitous class of emerging regulators underlying bacterial adaptation to environmental stressors. Until relatively recently, small open reading frames encoding these proteins were not designated genes in genome annotations. Therefore, our understanding of small protein biology was primarily limited to a few candidates associated with previously characterized larger partner proteins. Following the first systematic analyses of small proteins in Escherichia coli over a decade ago, numerous small proteins across different bacteria have been uncovered. An estimated one-third of these newly discovered proteins in

Indexed as

Anti-Bacterial AgentsBacteriaBacterial Outer Membrane ProteinsCell MembraneGene Expression Regulation, BacterialAnti-Bacterial AgentsBacterial Outer Membrane Proteinscell divisiongene regulationmembrane protein regulatorsrespiratory complexsignal transductionsmall proteinssporulationstress responsetoxin-antitoxin systemtransport

Identifiers

PMID34516282
PMCPMC8765417
OpenAlexW3198995132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.