Evidence map›Paper›PMID 34516280›Full record

ArticleJournal of bacteriology2021

Novel Amiloride Derivatives That Inhibit Bacterial Motility across Multiple Strains and Stator Types.

M I Islam, J H Bae, T Ishida, P Ridone, J Lin, M J Kelso, Y Sowa, B J Buckley, M A B Baker

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

M I Islam *School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
J H Bae *School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
T Ishida *Department of Frontier Bioscience, Hosei Universitygrid.257114.4, Tokyo, Japan.
P RidoneSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
J LinSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
M J KelsoMolecular Horizons, University of Wollongonggrid.1007.6, Wollongong, New South Wales, Australia.
Y SowaDepartment of Frontier Bioscience, Hosei Universitygrid.257114.4, Tokyo, Japan.ORCID 0000-0002-1691-2018
B J BuckleyMolecular Horizons, University of Wollongonggrid.1007.6, Wollongong, New South Wales, Australia.ORCID 0000-0002-8346-3371
M A B BakerSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-5839-6904
UNSW Sydney · AUHosei University · JPUniversity of Wollongong · AUCommonwealth Scientific and Industrial Research Organisation · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bacterial flagellar motor (BFM) is a protein complex that confers motility to cells and contributes to survival and virulence. The BFM consists of stators that are ion-selective membrane protein complexes and a rotor that directly connects to a large filament, acting as a propeller. The stator complexes couple ion transit across the membrane to torque that drives rotation of the motor. The most common ion gradients that drive BFM rotation are protons (H

Indexed as

Acid Sensing Ion Channel BlockersAmilorideEscherichia coliMovementVibrio alginolyticusAcid Sensing Ion Channel BlockersAmiloridephenylamilamilorideantimicrobial agentsbacterial flagellar motorbacterial motilityflagellar motilityion channelsmotilitysodium channel blockerstatorvirulence

Identifiers

PMID34516280
PMCPMC8544414
OpenAlexW3199687073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.