Evidence map›Paper›PMID 34515960›Full record

ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2021

Determinants of Functional Improvement After Cardiac Rehabilitation in Acute Coronary Syndrome.

Sofia Bianchi, Alessandro Maloberti, Alessio Peretti, Laura Garatti, Matteo Palazzini, Lucia Occhi, Ilaria Bassi, Sabrina Sioli, Marco Biolcati, Valentina Giani and 6 more

Open access · hybridAbstract read
In one paragraph

Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Article
  5. Article
  6. Cardiac Rehabilitation After Open Heart Surgery: A Narrative Systematic Review.Journal of cardiovascular development and disease · 2024
    Review
  7. Review
  8. Article
  9. Article
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  11. Secondary Prevention and Extreme Cardiovascular Risk Evaluation (SEVERE-1), Focus on Prevalence and Associated Risk Factors: The Study Protocol.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023
    Article
  12. Article
  13. Article
  14. "Medical Assistance in Contextual Awareness" (AMICO): A Project for a Better Quality of Care for Patients in Cardiac Rehabilitation Unit.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022
    Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Sofia BianchiSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Alessandro MalobertiSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy. alessandro.maloberti@ospedaleniguarda.it.ORCID http://orcid.org/0000-0002-2612-6264
Alessio PerettiSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Laura GarattiSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Matteo PalazziniSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Lucia OcchiDipartimento A. De Gasperis, Cardiac Rehabilitation, Cardiology 4, Niguarda Hospital, Piazza Ospedale Maggiore 3, 20159, Milan, Italy.
Ilaria BassiDipartimento A. De Gasperis, Cardiac Rehabilitation, Cardiology 4, Niguarda Hospital, Piazza Ospedale Maggiore 3, 20159, Milan, Italy.
Sabrina SioliDipartimento A. De Gasperis, Cardiac Rehabilitation, Cardiology 4, Niguarda Hospital, Piazza Ospedale Maggiore 3, 20159, Milan, Italy.
Marco BiolcatiSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Valentina GianiSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Massimiliano MonticelliSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Filippo LeidiSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Giacomo RuzzenentiSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Giovanna BerettaRehabilitative Medicine and Neuro-Rehabilitation, Niguarda Hospital, Milan, Italy.
Cristina GiannattasioSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Salvatore RiccobonoDipartimento A. De Gasperis, Cardiac Rehabilitation, Cardiology 4, Niguarda Hospital, Piazza Ospedale Maggiore 3, 20159, Milan, Italy.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITOspedale Maggiore · ITUniversity of Milano-Bicocca · IT

Funding

ministero dell'istruzione, dell'università e della ricerca Department of Excellence project PREMIA (PREcision MedIcine Approach: bringing biomarker research to clinic)
6 · The paper itself

Abstract

introductionCardiac rehabilitation (CR) is an effective tool for secondary prevention after acute coronary syndrome (ACS).

aimAim of our study was to find the significant determinants of exercise capacity (evaluated with the six-minute walking test-6-MWT) and functional improvement in patients undergoing CR after an ACS.

methodsThe study group included 298 patients (mean age 61.6 ± 10.2 years; males 80.2%) who, after ACS, were enrolled in CR program at Niguarda Hospital in Milan from 2015 to 2018. For all patients, we collected anamnestic, clinical and instrumental cardiological data. All patients performed a 6-MWT at the beginning (6-MWT-1) and at the end (6-MWT-2) of CR program. Δ meters were used to represent functional improvement.

resultsMultiple linear regression models were carried out for 6-MWT-1, 6-MWT-2, Δ meters and % Δ meters. Standardized regression coefficients showed that age (β = - 0.237; p < 0.001), BMI (β = - 0.116; p = 0.006) and heart rate (β = - 0.082; p = 0.040) were determinants of exercise capacity (6MWT-1 and 2), whereas age (β = -.231; p = 0.004), sex (β = - 0.187; p = 0.008) and BMI (β = - 0.164; p = 0.022) were determinants of functional improvement (Δ meters).

conclusionsOur data showed that functional improvement after CR in ACS patients is mainly related to non-cardiological variables. Instead it is related to intrinsic factors, both modifiable (BMI) and non-modifiable (age, sex).

Indexed as

Acute Coronary SyndromeCardiac RehabilitationPhysical Functional PerformanceAgedFemaleHumansMaleMiddle AgedTreatment OutcomeAcute coronary syndromeCardiac rehabilitationFunctional improvement

Identifiers

PMID34515960
PMCPMC8590661
OpenAlexW3200492543

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.