Evidence map›Paper›PMID 34515951›Full record

ArticleDrug delivery and translational research2022

Preparation, characterization, and in vivo evaluation of levonorgestrel-loaded thermostable microneedles.

Baorui Wang, Suohui Zhang, Xiaoyu Zhao, Jie Lian, Yunhua Gao

Abstract read
PubMed Publisher
In one paragraph

Article in Drug delivery and translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Baorui WangTechnical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.
Suohui ZhangTechnical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, China. suohuizhang@mail.ipc.ac.cn.ORCID 0000-0003-3970-2096
Xiaoyu ZhaoTechnical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.
Jie LianCollege of Investigation, Peoples Public, Security University of China, Beijing, 100038, China.
Yunhua GaoTechnical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.
Chinese Academy of Sciences · CNChina People's Public Security University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To facilitate the storage and use of poly (lactic-co-glycolic acid) (PLGA)-based microneedles (MNs) in hot seasons and regions, thermally stable MNs loaded with levonorgestrel (LNG) were developed. Due to its good biocompatibility and high glass transition temperature (T

Indexed as

Drug Delivery SystemsLevonorgestrelAdministration, CutaneousAnimalsMicePolymersRatsSkinLevonorgestrelPolymersHydroxypropyl methylcelluloseLong-acting contraceptiveThermal stabilityTransdermal drug delivery

Identifiers

PMID34515951
OpenAlexW3199837953

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.