Evidence map›Paper›PMID 34515844›Full record

ReviewApplied microbiology and biotechnology2021

An overview of D-galactose utilization through microbial fermentation and enzyme-catalyzed conversion.

Qiuming Chen, Wei Xu, Hao Wu, Cuie Guang, Wenli Zhang, Wanmeng Mu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Microorganisms · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qiuming ChenState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi , 214122, Jiangsu, China.
Wei XuState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi , 214122, Jiangsu, China.
Hao WuState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi , 214122, Jiangsu, China.
Cuie GuangState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi , 214122, Jiangsu, China. guang1226@jiangnan.edu.cn.
Wenli ZhangState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi , 214122, Jiangsu, China. wenlizhang@jiangnan.edu.cn.ORCID http://orcid.org/0000-0002-7861-0170
Wanmeng MuState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi , 214122, Jiangsu, China.

Funding

Natural Science Foundation of China 31801583Natural Science Foundation of China 31922073Natural Science Foundation of China 32001636Natural Science Foundation of Jiangsu Province BK20180607Natural Science Foundation of Jiangsu Province BK20200594Zhangjiagang international cooperation project ZKH1905
6 · The paper itself

Abstract

D-Galactose is an abundant carbohydrate monomer in nature and widely exists in macroalgae, plants, and dairy wastes. D-Galactose is useful as a raw material for biomass fuel production or low-calorie sweetener production, attracting increased attention. This article summarizes the studies on biotechnological processes for galactose utilization. Two main research directions of microbial fermentation and enzyme-catalyzed conversion from galactose-rich biomass are extensively reviewed. The review provides the recent discoveries for biofuel production from macroalgae, including the innovative methods in the pretreatment process and technological development in the fermentation process. As modern people pay more attention to health, enzyme technologies for low-calorie sweetener production are more urgently needed. D-Tagatose is a promising low-calorie alternative to sugar. We discuss the recent studies on characterization and genetic modification of L-arabinose isomerase to improve the bioconversion of D-galactose to D-tagatose. In addition, the trends and critical challenges in both research directions are outlined at the end. KEY POINTS: • The value and significance of galactose utilization are highlighted. • Biofuel production from galactose-rich biomass is accomplished by fermentation. • L-arabinose isomerase is a tool for bioconversion of D-galactose to D-tagatose.

Indexed as

BiotechnologyGalactoseCatalysisFermentationHumansGalactoseBiofuelD-GalactoseD-TagatoseFermentationL-Arabinose isomerase

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.