ArticleJournal of dental research2022
Ultrasonographic Tissue Perfusion in Peri-implant Health and Disease.
Article in Journal of dental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Laser doppler flowmetry as a diagnostic tool to detect gingival inflammation: a systematic review.BMC oral health · 2025Pooled it
- A systematic review of oral wound healing indices.PloS one · 2024Pooled it
- Cyanoacrylate Adhesive in Free Gingival Graft Healing: A Digital and Microcirculatory Randomized Clinical Trial.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025Trial
- Tissue Perfusion and Biomarkers Assessment Following Root Coverage Procedures.Journal of periodontal research · 2025Trial
- Characterization of oral biomarkers during early healing at augmented dental implant sites.Journal of periodontal research · 2025Trial
- Doppler ultrasonographic evaluation of tissue revascularization following connective tissue graft at implant sites.Journal of clinical periodontology · 2025Trial
- Recombinant human platelet-derived growth factor improves root coverage of a collagen matrix for multiple adjacent gingival recessions: A triple-blinded, randomized, placebo-controlled trial.Journal of clinical periodontology · 2022Trial
- Agreement Between Cone Beam Computed Tomography, Bone Sounding, Pulse-Echo Ultrasound, and Caliper Measurements for Gingival Thickness Assessment: A Method-Comparison Study.Dentistry journal · 2026Article
- Emerging, personalized, and minimally invasive technologies for periodontal and peri-implant soft and hard tissue regenerative therapy.Journal of periodontology · 2026Review
- New technologies in oral reconstructive medicine: Consensus report of the AAP/OF/SEPA Workshop.Journal of periodontology · 2026Article
- Implant-related orofacial pain managed with implant apicoectomy: A case report.Clinical advances in periodontics · 2026Article
- Flap perfusion of superficial split flap design for guided bone regeneration: A case report with ultrasonography.Clinical advances in periodontics · 2026Article
- Advancing the diagnosis of peri-implant diseases: From histological foundations to next-generation ultrasonographic diagnostic markers.Journal of periodontology · 2026Review
- Ultrasound-based assessment of peri-implant mucosal thickness: an ex vivo comparative study with artificial intelligence-assisted image analysis.BMC oral health · 2026Article
- Quantification of Supracrestal Tissue Attachment Using High-Frequency Ultrasound.Dento maxillo facial radiology · 2026Article
- Correlations between early ultrasound markers and the outcomes of staged lateral guided bone regeneration.Journal of periodontal & implant science · 2026Article
- Peri-Implant Soft-Tissue Phenotype Modification for Refractory Peri-Implant Mucositis: A 12-Month Prospective Clinical Study With Ultrasonographic Analysis.Journal of periodontal research · 2026Observational
- Comparative evaluation of direct and digital measurements of peri-implant defects using CBCT, ultrasound, and intraoral scanning.Dento maxillo facial radiology · 2026Article
- Innovations in microsurgery: The role of non-invasive blood perfusion imaging-A review and framework.Clinical advances in periodontics · 2026Review
- Impact of Peri-Implant Phenotype on Implant Therapy Outcomes: A 5-Year Cohort Analysis on Soft Tissue-Level Implants.Journal of clinical periodontology · 2026Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Color flow ultrasonography has played a crucial role in medicine for its ability to assess dynamic tissue perfusion and blood flow variations as an indicator of a pathologic condition. While this feature of ultrasound is routinely employed in various medical fields, its intraoral application for the assessment of tissue perfusion at diseased versus healthy dental implants has never been explored. We tested the hypothesis that quantified tissue perfusion of power Doppler ultrasonography correlates with the clinically assessed inflammation of dental implants. Specifically, we designed a discordant-matched case-control study in which patients with nonadjacent dental implants with different clinical diagnoses (healthy, peri-implant mucositis, or peri-implantitis) were scanned and analyzed with real-time ultrasonography. Forty-two posterior implants in 21 patients were included. Ultrasound scans were obtained at the implant regions of midbuccal, mesial/distal (averaged as interproximal), and transverse to compute the velocity- and power-weighted color pixel density from color velocity (CV) and color power (CP), respectively. Linear mixed effect models were then used to assess the relationship between the clinical diagnoses and ultrasound CV and CP. Overall, the results strongly suggested that ultrasound's quantified CV and CP directly correlate with the clinical diagnosis of dental implants at health, peri-implant mucositis, and peri-implantitis. This study showed for the first time that ultrasound color flow can be applicable in the diagnosis of peri-implant disease and can act as a valuable tool for evaluating the degree of clinical inflammation at implant sites.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.