Evidence map›Paper›PMID 34515489›Full record

ReviewJournal of proteome research2021

Native Structural and Functional Proteoform Characterization of the Prolyl-Alanyl-Specific Endoprotease EndoPro from

Guusje van Schaick, Elena Domínguez-Vega, Christoph Gstöttner, Johanna H van den Berg-Verleg, Olaf Schouten, Michiel Akeroyd, Maurien M A Olsthoorn, Manfred Wuhrer, Albert J R Heck, Nicolas Abello and 1 more

Abstract readReview
In one paragraph

Review in Journal of proteome research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Guusje van SchaickLeiden University Medical Center, Center for Proteomics and Metabolomics, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.ORCID 0000-0001-8320-4460
Elena Domínguez-VegaLeiden University Medical Center, Center for Proteomics and Metabolomics, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.ORCID 0000-0002-6394-0783
Christoph GstöttnerLeiden University Medical Center, Center for Proteomics and Metabolomics, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
Johanna H van den Berg-VerlegDSM Biotechnology Center, Center for Enabling Innovation, Alexander Fleminglaan 1, 2613 AX, Delft, The Netherlands.
Olaf SchoutenDSM Biotechnology Center, Center for Enabling Innovation, Alexander Fleminglaan 1, 2613 AX, Delft, The Netherlands.
Michiel AkeroydDSM Biotechnology Center, Center for Enabling Innovation, Alexander Fleminglaan 1, 2613 AX, Delft, The Netherlands.
Maurien M A OlsthoornDSM Biotechnology Center, Center for Enabling Innovation, Alexander Fleminglaan 1, 2613 AX, Delft, The Netherlands.
Manfred WuhrerLeiden University Medical Center, Center for Proteomics and Metabolomics, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.ORCID 0000-0002-0814-4995
Albert J R HeckBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH, Utrecht, The Netherlands.ORCID 0000-0002-2405-4404
Nicolas AbelloDSM Biotechnology Center, Center for Enabling Innovation, Alexander Fleminglaan 1, 2613 AX, Delft, The Netherlands.
Vojtech FrancBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH, Utrecht, The Netherlands.ORCID 0000-0003-4114-2382

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prolyl-alanyl-specific endoprotease (EndoPro) is an industrial enzyme produced in

Indexed as

Aspergillus nigerProteomicsGlycosylationMass SpectrometryProteinsProteinsanion exchange chromatographymass spectrometrynative separationprolyl-alanyl-specific endoproteasestructure−function relationship

Identifiers

PMID34515489
PMCPMC8491274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.