Evidence map›Paper›PMID 34515386›Full record

ArticleBrain pathology (Zurich, Switzerland)2022

Hispano-American Brain Bank on Neurodevelopmental Disorders: An initiative to promote brain banking, research, education, and outreach in the field of neurodevelopmental disorders.

Brett D Dufour, Lilia Albores-Gallo, Jose Luna-Muñoz, Randi Hagerman, Amaya Miquelajauregui, Efrain Buriticá, Wilmar Saldarriaga, Mar Pacheco-Herrero, Ana Yris Silvestre-Sosa, Carla Mazefsky and 7 more

Abstract readLetter
In one paragraph

Article in Brain pathology (Zurich, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Brett D DufourDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, Sacramento, California, USA.
Lilia Albores-GalloDepartment of Genetic, Clinical, and Community Epidemiology, Hospital Psiquiátrico Infantil "Dr. Juan N. Navarro", Universidad Nacional Autónoma de Mexico, México City, México.
Jose Luna-MuñozNational Dementia BioBank, Ciencias Biológicas, Facultad de Estudios Superiores, Cuautitlán, Universidad Nacional Autónoma de Mexico, México City, México.
Randi HagermanDepartment of Pediatrics, UC Davis School of Medicine, Sacramento, California, USA.
Amaya MiquelajaureguiInstitute of Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Efrain BuriticáDepartment of Morphology, Centro de Estudios Cerebrales, Faculty of Health, University of Valle, Cali, Colombia.
Wilmar SaldarriagaUniversidad del valle, Hospital Universitario del Valle, Cali, Colombia.
Mar Pacheco-HerreroNeuroscience Research Laboratory, Faculty of Health Sciences, Pontificia Universidad Católica Madre y Maestra, Santiago de los Caballeros, Dominican Republic.
Ana Yris Silvestre-SosaHospital Santo Socorro, Santo Domingo, Dominican Republic.
Carla MazefskyDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Holly GastgebDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Julia KoflerDepartment of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Manuel CasanovaDepartment of Biomedical Sciences, School of Medicine Greenville, University of South Carolina, Greenville, South Carolina, USA.
Patrick R HofNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Eric LondonNew York State Institute for Basic Research, Staten Island, New York, USA.
Paul HagermanMIND Institute, UC Davis School of Medicine, Sacramento, California, USA.
Verónica Martínez-CerdeñoDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, Sacramento, California, USA.ORCID 0000-0002-9613-3603

Funding

Interdisciplinary Training for Autism Researchers(RMI)T32MH073124 · NIMH · UNIVERSITY OF CALIFORNIA DAVIS · PI Stephen Charles Noctor, Christine Wu Nordahl · 2004 to 2026
$6.8M
Cortical and subcortical chandelier cell pathophysiology and symptomatology in autismR01MH094681 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Veronica Martinez-Cerdeno · 2011 to 2026
$6.5M
Fragile X-associated tremor/ataxia syndrome (FXTAS) pathology and anatomy: imaging and clinical correlatesR01NS107131 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MARTINEZ-CERDENO, VERONICA · 2018 to 2022
$2.6M
NIMH NIH HHS R01 MH094681NIMH NIH HHS T32 MH073124NINDS NIH HHS R01 NS107131
6 · The paper itself

Abstract

Neurodevelopmental disorders (NDDs) are conditions that present with brain dysfunction due to alterations in the processes of brain development. They present with neuropsychiatric, cognitive, and motor symptoms. Autism spectrum disorder (ASD) and Fragile X syndrome (FXS) are two of the most common NDDs. Human brain tissue is a scarce resource that is obtained from postmortem donations. In the case of NDDs, specifically autism, the reduced donation rate of brains prevents researchers to investigate its pathology and fine anatomy. The Hispano-American Brain Bank of Neurodevelopmental Disorders (Banco Hispanoamericano de CErebros de trastornos del NEurodesarrollo) or CENE is a large-scale brain bank for neurodevelopmental disorders in Hispano-America and the US. CENE's objectives are to collect and distribute brains of patients with NDDS, with a focus on ASD and FXS, to perform research, promote education of future scientists, and enhance public awareness about the importance of human tissue availability for scientific research on brain function and disease. CENE has thus far established a bilingual system of nodes and teams in several American countries including California-US, Pennsylvania-US, México, Puerto Rico, Colombia, and Dominican Republic. CENE ensures that postmortem NDD samples used in research better match the world's genetic and ethnic diversity. CENE enables and expands NDD brain research worldwide, particularly with respect to ASD and FXS.

Indexed as

Autism Spectrum DisorderAutistic DisorderNeurodevelopmental DisordersBrainHumansautismbrain bankDown syndromeFragile X syndromeLatinoamericaneurodevelopmental disorders

Identifiers

PMID34515386
PMCPMC8877728

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.