Evidence map›Paper›PMID 34514870›Full record

ReviewPhysiology (Bethesda, Md.)2022

Immune Sexual Dimorphism: Connecting the Dots.

Shani Talia Gal-Oz, Tal Shay

Abstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Sex and the Developmental Environment Shape Molecular Networks Underlying Bronchial Responsiveness in Mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Microheterogeneity in the Kinetics and Sex-Specific Response to Type I IFN.Journal of immunology (Baltimore, Md. : 1950) · 2024
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shani Talia Gal-OzDepartment of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.ORCID 0000-0001-7775-2006
Tal ShayDepartment of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.ORCID 0000-0003-0755-1350

Funding

ImmGen: Gene Expression and Regulation in Immune CellsR24AI072073 · NIAID · JOSLIN DIABETES CENTER · PI CHRISTOPHE O. BENOIST · 2007 to 2026
$28.5M
NIAID NIH HHS R24 AI072073
6 · The paper itself

Abstract

Despite numerous studies of immune sexual dimorphism, sexual differences are not rigorously mapped and dimorphic mechanisms are incompletely understood. Current immune research typically studies sex differences in specific cells, tissues, or diseases but without providing an integrated picture. To connect the dots, we suggest comprehensive research approaches to better our understanding of immune sexual dimorphism and its mechanisms.

Indexed as

Sex CharacteristicsFemaleHumansMaleimmune systemsexual dimorphism

Identifiers

PMID34514870
PMCPMC8873034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.