Evidence map›Paper›PMID 34514757›Full record

ArticleJournal of Zhejiang University. Science. B

Pulsed low-dose rate radiotherapy has an improved therapeutic effect on abdominal and pelvic malignancies.

Xin Wen, Hui Qiu, Zhiying Shao, Guihong Liu, Nianli Liu, Aoxing Chen, Xingying Zhang, Xin Ding, Longzhen Zhang

Open access · greenAbstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Xin WenDepartment of Radiation Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Hui QiuDepartment of Radiation Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Zhiying ShaoDepartment of Interventional Ultrasound, Zhejiang Cancer Hospital, Hangzhou 310000, China.
Guihong LiuDepartment of Radiation Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Nianli LiuCancer Institute of Xuzhou Medical University, Xuzhou 221000, China.
Aoxing ChenDepartment of Radiation Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Xingying ZhangDepartment of Radiation Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.
Xin DingDepartment of Radiation Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China. dingxin81@163.com.
Longzhen ZhangCancer Institute of Xuzhou Medical University, Xuzhou 221000, China. jsxyfyzlz@126.com.
Xuzhou Medical College · CNJiangsu University · CNZhejiang Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Until now, there has been a lack of standard and effective treatments for patients with recurrent malignant tumors or abdominal and pelvic malignancies with extensive invasion (Morris, 2000). Generally, these patients face problems such as inability to undergo surgery or chemotherapy resistance (Combs et al., 2016). Re-radiotherapy has achieved a prominent place in the treatment of patients who have received radiotherapy previously and developed in-field recurrences (Straube et al., 2018). However, re-radiotherapy is very complicated, requiring comprehensive consideration of appropriate radiation dose, interval from first radiotherapy, boundary of the radiotherapy target area, and damage to surrounding normal tissues (Straube et al., 2019). In other words, it is necessary to focus on the protection of surrounding normal tissues while maximizing the efficacy of re-radiotherapy in such patients.

Indexed as

Abdominal NeoplasmsAnimalsDNA DamageHumansMaleMiceMice, Inbred BALB CPelvic NeoplasmsRadiotherapy DosageAbdominal and pelvic cancersHRS/IRRPLDRT1/2

Identifiers

PMID34514757
PMCPMC8435343
OpenAlexW3201042275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.