Evidence map›Paper›PMID 34514697›Full record

ReviewDiabetes/metabolism research and reviews2022

Erectile dysfunction and diabetes: A melting pot of circumstances and treatments.

Giuseppe Defeudis, Rossella Mazzilli, Marta Tenuta, Giovanni Rossini, Virginia Zamponi, Soraya Olana, Antongiulio Faggiano, Paolo Pozzilli, Andrea M Isidori, Daniele Gianfrilli

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Diabetes/metabolism research and reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed, 7 pooled it
23.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 7 syntheses or guidelines pooled it, 264 citations in OpenAlex.

  1. Pooled it
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  12. Review
  13. Development of a predictive model for postoperative erectile function recovery in male patients with incomplete traumatic cervical spinal cord injury.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  14. Article
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  17. Retinal vascular and structural changes in men with erectile dysfunction: a systematic review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
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95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Giuseppe DefeudisUnit of Endocrinology and Diabetes, Department of Medicine, University Campus Bio-Medico di Roma, Rome, Italy.ORCID 0000-0003-2425-5609
Rossella MazzilliDepartment of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Marta TenutaDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Giovanni RossiniUnit of Endocrinology and Diabetes, Department of Medicine, University Campus Bio-Medico di Roma, Rome, Italy.
Virginia ZamponiDepartment of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Soraya OlanaDepartment of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Antongiulio FaggianoDepartment of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Paolo PozzilliUnit of Endocrinology and Diabetes, Department of Medicine, University Campus Bio-Medico di Roma, Rome, Italy.ORCID 0000-0001-5090-636X
Andrea M IsidoriDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Daniele GianfrilliDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · ITUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus (DM), a chronic metabolic disease characterised by elevated levels of blood glucose, is among the most common chronic diseases. The incidence and prevalence of DM have been increasing over the years. The complications of DM represent a serious health problem. The long-term complications include macroangiopathy, microangiopathy and neuropathy as well as sexual dysfunction (SD) in both men and women. Erectile dysfunction (ED) has been considered the most important SD in men with DM. The prevalence of ED is approximately 3.5-fold higher in men with DM than in those without DM. Common risk factors for the development of DM and its complications include sedentary lifestyle, overweight/obesity and increased caloric consumption. Although lifestyle changes may help improve sexual function, specific treatments are often needed. This study aims to review the definition and prevalence of ED in DM, the impact of DM complications and DM treatment on ED and, finally, the current and emerging therapies for ED in patients with DM.

Indexed as

Diabetes ComplicationsDiabetes MellitusDiabetes Mellitus, Type 2Erectile DysfunctionBlood GlucoseFemaleHumansMalePrevalenceRisk FactorsBlood Glucosediabetesdiabetes complicationsdiabetes treatmenterectile dysfunctionhypogonadismPDE5 inhibitors

Identifiers

PMID34514697
PMCPMC9286480
OpenAlexW3199642017

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.