ArticleEuropean heart journal. Case reports2021
Case report: acute myocarditis following the second dose of mRNA-1273 SARS-CoV-2 vaccine.
Article in European heart journal. Case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Cardiac MRI Findings in COVID-19 Vaccine-Related Myocarditis: A Pooled Analysis of 468 Patients.Journal of magnetic resonance imaging : JMRI · 2022Pooled it
- Myocarditis after COVID-19 mRNA vaccination: A systematic review of case reports and case series.Clinical cardiology · 2022Pooled it
- Myocarditis Following COVID-19 Vaccination: A Systematic Review of Case Reports.The Yale journal of biology and medicine · 2022Pooled it
- Cardiac and Neurological Complications Post COVID-19 Vaccination: A Systematic Review of Case Reports and Case Series.Vaccines · 2024Review
- COVID-19 mRNA vaccine-related myocarditis: A PRISMA systematic review, imaging approach and differential diagnoses.Radiology case reports · 2024Article
- Self-DNA driven inflammation in COVID-19 and after mRNA-based vaccination: lessons for non-COVID-19 pathologies.Frontiers in immunology · 2023Article
- Autoimmune and autoinflammatory conditions after COVID-19 vaccination. New case reports and updated literature review.Journal of autoimmunity · 2022Review
- Severe Myocarditis in a Female Following mRNA-1273 Vaccine: A Case Report and Review of the Literature.Cureus · 2022Article
- Rare Heterogeneous Adverse Events Associated with mRNA-Based COVID-19 Vaccines: A Systematic Review.Medicines (Basel, Switzerland) · 2022Review
- Clinical Characteristics of Patients with Myocarditis following COVID-19 mRNA Vaccination: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Article
- Myocarditis Following COVID-19 Vaccination: Cardiac Imaging Findings in 118 Studies.Tomography (Ann Arbor, Mich.) · 2022Review
- Review
- Two Cases of Acute Myocarditis in Young Male Adults After mRNA Vaccines Against COVID-19: Similarities and Differences.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2022Article
- Cardiovascular manifestations secondary to COVID-19: A narrative review.Respiratory medicine and research · 2022Review
- Development of myocarditis and pericarditis after COVID-19 vaccination in adult population: A systematic review.Annals of medicine and surgery (2012) · 2022Review
- Review
- Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review.Frontiers in cardiovascular medicine · 2022Article
- Clinical presentation and cardiac imaging findings in patient cases of perimyocarditis and pericarditis with a temporal association to SARS-CoV-2 vaccination.Frontiers in cardiovascular medicine · 2022Article
- Case Report: Cytomegalovirus Reactivation and Pericarditis Following ChAdOx1 nCoV-19 Vaccination Against SARS-CoV-2.Frontiers in immunology · 2021Article
- Cardiovascular complications of COVID-19 vaccines: A review of case-report and case-series studies.Heart & lung : the journal of critical careReview
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe SARS-CoV-2 pandemic has led to the development of the first mRNA vaccines used in humans. The vaccines are well tolerated, safe, and highly efficacious; however, post-marketing surveillance is revealing potential rare adverse effects. We report a case of symptomatic acute myocarditis following administration of the second dose of mRNA-1273 SARS-CoV-2 vaccine. CASE SUMMARY: A 44-year-old man presented with chest pain and ST-segment elevation 4 days after receiving the second dose of mRNA-1273 SARS-CoV-2 Vaccine. Emergent coronary angiogram showed minimal coronary artery disease. Cardiac magnetic resonance imaging confirmed acute myocarditis. Diagnosis of vaccine-associated myocarditis was made given the temporal relationship and supportive treatment initiated. Follow-up at 1 month confirmed complete symptomatic recovery and echocardiogram demonstrated normalization of cardiac function. DISCUSSION: Acute myocarditis should be considered in patients who present with chest pain or dyspnoea within days of receiving mRNA-1273 SARS-CoV-2 vaccination, especially after the second dose. This may be managed successfully with supportive therapies with complete recovery of cardiac function and symptoms. Further research is warranted to determine the mechanisms by which mRNA vaccines may cause myocarditis and for potential long-term cardiovascular injury.
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