Evidence map›Paper›PMID 34514290›Full record

ArticlePlant direct2021

Multiplex genome editing in

William T Jordan, Seth Currie, Robert J Schmitz

Open access · goldAbstract read
In one paragraph

Article in Plant direct, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Wheat's Up with CRISPR-Cas-Current Advances, Obstacles and Perspectives.International journal of molecular sciences · 2026
    Review
  2. Review
  3. Review
  4. A comprehensive review onFrontiers in genetics · 2024
    Review
  5. Review
  6. Review
  7. Article
  8. Multiplex genome editing inPlant direct · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

William T JordanDepartment of Genetics University of Georgia Athens Georgia USA.
Seth CurrieDepartment of Genetics University of Georgia Athens Georgia USA.ORCID https://orcid.org/0000-0002-0047-1545
Robert J SchmitzDepartment of Genetics University of Georgia Athens Georgia USA.ORCID https://orcid.org/0000-0001-7538-6663
University of Georgia · US

Funding

T32 Predoctoral training grant in geneticsT32GM007103 · NIGMS · UNIVERSITY OF GEORGIA (UGA) · PI DYER, KELLY A · 1985 to 2021
$5.9M
NIGMS NIH HHS T32 GM007103
6 · The paper itself

Abstract

The use of CRISPR-Cas proteins for the creation of multiplex genome engineering represents an important avenue for crop improvement, and further improvements for creation of knock-in plant lines via CRISPR-based technologies may enable the high-throughput creation of designer alleles. To circumvent limitations of the commonly used CRISPR-Cas9 system for multiplex genome engineering, we explored the use of

Indexed as

ArabidopsisCas12aCpf1CRISPRgene editingMb3Cas12a

Identifiers

PMID34514290
PMCPMC8421513
OpenAlexW3196542608

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.