Evidence map›Paper›PMID 34514200›Full record

ArticleKidney international reports2021

The Role of Vascular Lesions in Diabetes Across a Spectrum of Clinical Kidney Disease.

Rosa Rodríguez-Rodríguez, Radovan Hojs, Francesco Trevisani, Enrique Morales, Gema Fernández, Sebastjan Bevc, Clara María Cases Corona, Josep María Cruzado, María Quero, Maruja Navarro Díaz and 20 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

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  7. Heterogeneous afferent arteriolopathy: a key concept for understanding blood pressure-dependent renal damage.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
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  15. A 90-Day Safety Study of Meat fromLife (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 17 institutions in 6 countries.

Rosa Rodríguez-RodríguezHospital Universitario de Canarias, Pathology Department, Tenerife, Spain.
Radovan HojsDepartment of Nephrology, Clinic for Internal Medicine, University Clinical Centre Maribor and Faculty of Medicine, University of Maribor, Slovenia.
Francesco TrevisaniIRCCS Ospedale San Raffaele, URI-Urological Research Institute, Milano, Italy.
Enrique MoralesHospital 12 de Octubre, Madrid, Spain.
Gema FernándezHospital Universitario Fundación Alcorcón, Madrid, Spain.
Sebastjan BevcDepartment of Nephrology, Clinic for Internal Medicine, University Clinical Centre Maribor and Faculty of Medicine, University of Maribor, Slovenia.
Clara María Cases CoronaHospital Universitario Fundación Alcorcón, Madrid, Spain.
Josep María CruzadoREDINREN ISCIII, Madrid, Spain.
María QueroREDINREN ISCIII, Madrid, Spain.
Maruja Navarro DíazHospital Germans Trias i Pujol, Barcelona, Spain.
Arianna BettigaIRCCS Ospedale San Raffaele, URI-Urological Research Institute, Milano, Italy.
Federico Di MarcoIRCCS Ospedale San Raffaele, URI-Urological Research Institute, Milano, Italy.
Marina López MartínezHospital Germans Trias i Pujol, Barcelona, Spain.
Francisco MoresoREDINREN ISCIII, Madrid, Spain.
Clara García GarroHospital Universitario Vall d'Hebron, Barcelona, Spain.
Khaled KhazimGalilee Medical Center, Nahariya, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Fedaa GhanemGalilee Medical Center, Nahariya, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Manuel PragaHospital 12 de Octubre, Madrid, Spain.
Meritxell IbernónHospital Sant Joan Despí Moisès Broggi, Barcelona, Spain.
Ivo LaranjinhaHospital de Santa Cruz Lisboa, Lisboa, Portugal.
Luís MendonçaCentro Hospitalar Lisboa Norte, Lisboa, Portugal.
Miguel Bigotte VieiraCentro Hospitalar São João, Porto, Portugal.
Mads HornumRigshospitalet, Copenhagen, Denmark.
Bo Feldt-RasmussenRigshospitalet, Copenhagen, Denmark.
Beatriz Fernández-FernándezREDINREN ISCIII, Madrid, Spain.
Patricia Fox ConcepciónResearch Unit, Hospital Universitario de Canarias, Tenerife, Spain.
Natalia Negrín MenaResearch Unit, Hospital Universitario de Canarias, Tenerife, Spain.
Alberto OrtizREDINREN ISCIII, Madrid, Spain.
Esteban PorriniUniversity of La Laguna, Faculty of Medicine, Tenerife, Spain.
DIABESITY working group of the ERA
Spanish Clinical Research Network · ESInstituto de Salud Carlos III · ESIRCCS Ospedale San Raffaele · ITHospital Universitari Germans Trias i Pujol · ESHospital Universitario de Canarias · ESRigshospitalet · DKWestern Galilee Hospital · ILCentro Hospitalar Lisboa Norte · PTHospital de Santa Cruz · PTHospital de Sant Joan Despí Moisès Broggi · ESHospital Universitario Fundación Alcorcón · ESResearch Institute Hospital 12 de Octubre · ESUniversidad Autónoma de Madrid · ESUniversidad de La Laguna · ESUniversity Clinical Centre Maribor · SIUniversity of Maribor · SIVall d'Hebron Hospital Universitari · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe clinical-histologic correlation in diabetic nephropathy is not completely known.

methodsWe analyzed nephrectomy specimens from 90 patients with diabetes and diverse degrees of proteinuria and glomerular filtration rate (GFR).

resultsThirty-six (40%) subjects had normoalbuminuria, 33 (37%) microalbuminuria, and 21 (23%) non-nephrotic proteinuria. Mean estimated GFR (eGFR) was 65±23 (40% <60 ml/min per 1.73 m

conclusionsWeak correspondence between analytical parameters and kidney histology was found. Thus, disease may progress undetected from the early clinical stages of the disease. Finally, vascular damage was a very common finding, which highlights the role of ischemic intrarenal disease in diabetes.

Indexed as

albuminuriachronic kidney diseasediabetesdiabetic nephropathyhistologynormoalbuminuria

Identifiers

PMID34514200
PMCPMC8419124
OpenAlexW3172749451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.